Welcome. This is Mårten Linds homepage.
I am a molecular biologist/geneticist with a special interest in fungal genomics and forest pathology. I have been at SLU since 1995 and at the department since 2001.
I’m currently working as a post-doc in the project “Understanding and preventing root rot of conifers”, which is funded by SSF and run by Jan Stenlid, Sara von Arnold and Bo Karlsson. I am studying the causal agent of root rot infections, Heterobasidion annosum, and try to identify candidate pathogenicity genes. This is done by combining a global transcriptome analysis, i.e investigating genes up-regulated during bark infection, with a genomic approach, i.e identifying QTLs for pathogenicity in a full-genome linkage map. Genes both expressed during infection and present within a pathogenicity QTL are considered strong candidates and probably plays an important part in the infection mechanism.
A linkage map this complete has a huge potential in the study of any measureable trait of the fungus and several other ongoing and finished projects have taken advantage of this. Traits such as growth rate, fungicide resistance and several types of intraspecific interactions have been attributed to QTLs across the genome, which can be investigated for candidates.
The first version of the linkage map and some early applications of it was the subject of my PhD-thesis which I defended at the department in November 2006.
Other ongoing projects include the role of the mitochondria during Heterobasidion infection, Heterobasidion tolerance towards several fungicides possibly being controlled by a single general genetic factor and the karyotyping of Heterobasidion chromosomes using pulse-field gel electrophoresis.
Lind, M. 2006. Genetics of Virulence and Intraspecific Interactions in Heterobasidion annosum s.l., Swedish University of Agricultural Sciences
Lind M, Källman T, Chen J, Ma XF, Bousquet J, Morgante M, Zaina G, Karlsson B, Elfstrand M, Lascoux M, Stenlid J. A Picea abies Linkage Map Based on SNP Markers Identifies QTLs for Four Aspects of Resistance to Heterobasidion parviporum Infection. PLoS One. 2014 Jul 18;9(7):e101049. doi: 10.1371/journal.pone.0101049.
Lind, M, Stenlid J, Olson, Å. 2014 Heterobasidion annosum s.l. genomics. In Francis Martin, editor: Fungi, Vol 70, ABR, UK: Academic Press, 2014, pp. 371-396.
van der Nest, M, Olson, A, Lind, M, Vélëz, H, Dalman, K, Brandström Durling, M, Karlsson, M, Stenlid, J. 2014. Distribution and evolution of het gene homologs in the basidiomycota. Fungal Genetics and Biology 64: 45-57
Dalman, K, Himmelstrand, K, Brandström-Durling, M, Lind, M, Olson, Å, Stenlid J. 2013. A genome-wide association study identifies genomic regions for virulence in Heterobasidion annosum s.s. PLoS ONE 8:1, e53525
Lind, M, van der Nest, M, Olson, Å, Brandström-Durling, M, Stenlid, J. 2012. A full 2nd generation linkage map of Heterobasidion annosum s.l. based on in silica anchoring of AFLP-markers. PLoS ONE 7:11, e48347
Olson, Å., Aerts, A., Asiegbu, F., Belbahri, L., Bouzid, O., Broberg, A., Canbäck, B., Coutinho, PM., Cullen, D., Dalman, K., Deflorio, G9, Linda T.A. van Diepen, LTA., Dunand, C., Duplessis, S., Durling, M., Gonthier, P., Grimwood, J., Fossdal, CG., , D., Henrissat, B., Hietala, A., Himmelstrand, K., Hoffmeister, D., Högberg, N., James, TY., Karlsson, M., Kohler, A., Kües, U., Lee, YH., Lin, YC., Lind, M., Lindquist, E., Lombard, V., Lucas, S., Lundén, K., Morin, E., Murat, C., Park, J., Raffaello, T., Rouzé, P., Salamov, A., Schmutz, J., Solheim, H., Ståhlberg, J., Vélëz, H., de Vries, RP., Wiebenga, A., Woodward, S., Yakovlev, I., Garbelotto, M., Martin, F., Grigoriev, IV., Stenlid, J. 2012. Insight into trade-off between wood decay and parasitism from the genome of a fungal forest pathogen. New Phytol. DOI:10.1111/j.1469-8137.2012.04128.x
Arnerup J, Lind M, Olson Å, Stenlid J, Elfstrand M. 2011. The pathogenic white-rot fungus Heterobasidion parviporum triggers non-specific defence responses in the bark of Norway spruce . Tree Physiology 2011 31: 1262-1272
Lind, M., Stenlid, J., and Olson, A. 2007. Genetics and QTL mapping of somatic incompatibility and intraspecific interactions in the basidiomycete Heterobasidion annosum s.l.. Fungal Genetics and Biology 44: 1242-51.
Lind, M., Dalman, K., Stenlid, J., Karlsson, B., and Olson, A. 2007. Identification of quantitative trait loci affecting virulence in the basidiomycete Heterobasidion annosum s.l..Current Genetics 52(1):35-44
Olson, A., Lind, M., and Stenlid, J. 2005. In vitro test of virulence in the progeny of a Heterobasidion interspecific cross. Forest Pathology 35(5):321-331
Lind M., Olson Å., Stenlid J. 2005. An AFLP-markers based genetic linkage map of Heterobasidion annosum locating intersterility genes. Fungal Genetics and Biology 42(6):519–527
Relevant articles in prep
Lind, M, Källman, T, Chen, J, Bousquet, J, Morgante, M, Zaina, G, Karlsson, B, Elfstrand, M, Lascoux, M and Stenlid, J. A saturated Picea abies linkage map based on SNP markers identifying QTLs for three traits of resistance to Heterobasidion parviporum infection. Submitted to PLoS ONE May 2014
Lind, M, Dalman, K, Brandström-Durling, M, Stenlid, J. A genome-wide association study identifies genomic regions for virulence in Heterobasidion parviporum. In prep.