Sveriges lantbruksuniversitet
Swedish University of Agricultural Sciences
Sveriges lantbruksuniversitet
Swedish University of Agricultural Sciences

Department of Forest Mycology and Plant Pathology

Sveriges lantbruksuniversitet
Swedish University of Agricultural Sciences

The Clonostachys rosea genome project

Fungal species belonging to the genera Clonostachys has been shown to be efficient antagonists against a range of plant pathogens, presumably due to their mycoparasitic lifestyle.

C. rosea protect plants from fungal diseases

In the mid 1990ies C. rosea strain IK726 was identified as a potential biocontrol agent against Fusarium disease on wheat and barley in a Danish program, starting with greenhouse experiments that were followed up with small field plots and large field experiments. Strain IK726 has been shown to be an efficient biocontrol agent under field conditions against a variety of plant diseases on agricultural crops, including diseases caused by Fusarium, Pythium, Botrytis, Alternaria, Tilletia and Bipolaris pathogens.

Investigating a three-way interaction

Our research is focused on understanding interaction mechanisms in the three-way interaction between C. rosea, fungal pathogens and host plants. We apply next-generation sequencing technology to sequence the genome and several transcriptomes of C. rosea strain IK726, as well as genetic transformation technology and comparative studies with Trichoderma biocontrol agents.

The Clonostachys rosea genome is now published in Genome Biology and Evolution and is available here.


Contact person

Dan Funck Jensen


Genomic resource: Clonostachys rosea v. 1.0

JGI (the Joint Genome Institute)

Improving industry through nature (popular science article)

Selected publications

Karlsson M, Brandström-Durling M et al.  (2015) Insights on the evolution of mycoparasitism from the genome of Clonostachys rosea. Genome Biology and Evolution 7:465-480.

Dubey M, Funck Jensen D, Karlsson M (2014) An ATP-binding cassette pleiotropic drug transporter protein is required for xenobiotic tolerance and antagonism in the fungal biocontrol agent Clonostachys rosea. Molecular Plant-Microbe Interactions 27:725–732.

Dubey M, Funck Jensen D, Karlsson M (2014) Hydrophobins are required for conidial hydrophobicity and plant root colonization in the fungal biocontrol agent Clonostachys rosea. BMC Microbiology 14:18.

Kosawang C, Karlsson M, Vélëz H, Have Rasmussen P, Collinge DB, Jensen B, Funck Jensen D (2014) Zearalenone detoxification by zearalenone hydrolase is important for the antagonistic ability of Clonostachys rosea against mycotoxigenic Fusarium graminearum. Fungal Biology 118:364-373.

Kosawang C, Karlsson M, Funck Jensen D, Dilokpimol A, Collinge DB (2014) Transcriptomic profiling to identify genes involved in Fusarium mycotoxin deoxynivalenol and zearalenone tolerance in the mycoparasitic fungus Clonostachys rosea. BMC Genomics 15:55.

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