Sveriges lantbruksuniversitet
Swedish University of Agricultural Sciences
Sveriges lantbruksuniversitet
Swedish University of Agricultural Sciences

Department of Forest Mycology and Plant Pathology

Sveriges lantbruksuniversitet
Swedish University of Agricultural Sciences

Heterobasidion genomics

The fungus Heterobasidion annosum species complex is common pathogens that causes root and but rot in conifer plantations and natural forests throughout the northern hemisphere.

Fruit body of Heterobasidion sp. Photo by Jonàs Oliva.

Within several genome projects we study its evolutionary history and biology including development, non self recognition, mating, and secondary metabolism. The genome projects will enable us to identifying pathogenicity determinants and get insights the mechanisms of its interactions with the host trees. The increased knowledge of the fungus will make an invaluable contribution to the possibility of controlling the disease.

People involved:

Jan Stenlid, Prof. 
Åke Olson, Ph.D.
Magnus Karlsson, Ph.D.
Mårten Lind, Ph.D.
Mikael Brandström-Durling, Ph.D.
Karl Lunden, Ph.D.
Eddy Vélëz, Ph.D.
Kerstin Dalman, Ph.D.
Kajsa Himmelstrand, Ph.D. student

Our projects:

  • A whole genome shotgun sequencing of the Heterobasidion irregularis (previously H. annosum North American P-type) in collaboration with an international consortium and performed at the Joint Genome Institute (JGI). A second version after finishing and gap closure of the genome is available.
  • The H. annosum s.s. are studied in a population re-sequencing project were 23 individuals been analysed using Solexa technology. Evolutionary history and genome evolution aspects will be analysed.
  • Other species with in the complex that we perform whole genome studies on include; H. occidentale, H. parviporum and H. abietinum.


Heterobasidion v2.0 (JGI)

Selected publications

Pathogenicity of Heterobasidion annosum
S-P hybrids is determined by mitochondria.

Å. Olson and J. Stenlid. 2001.
Nature 411: 438

Expressed sequences from the
basidiomycetous tree pathogen
Heterobasidion annosum during early

M. Karlsson et al. 2003.
Fungal Biology and Genetics 39: 51-59

An AFLP-marker based genetic linkage
map of Heterobasidion annosum locating
intersterility genes.
M. Lind et al. 2005.
Fungal Genetics and Biology 42: 519-527

Development of a rapid and simple
Agrobacterium tumefaciens-mediated
transformation system for the fungal
pathogen Heterobasidion annosum.
N. Samils et al.2006.
FEMS Microbiol. Lett. 255: 82-88

Identification of Quantitative Trait Loci
affecting virulence in the basidiomycete
Heterobasidion annosum sensu lato.
M. Lind et al. 2007.
Current Genetics 52: 35-44

Genetics and QTL mapping of somatic
incompatibility and interspecific
interactions in the basidiomycete
Heterobasidion annosum s.l.
M. Lind et al. 2007.
Fungal Genetics & Biology 44:1242-1251

Evolutionary significance of imbalanced
nuclear ratios within heterokaryons of the
basidiomycete fungus Heterobasidion
T.Y. James et al. 2008.
Evolution 62, 2279-2296
Evolutionary history of the conifer root
rot fungus Heterobasidion annosum
sensu lato.
K. Dalman et al. 2010.
Molecular Ecology, in press 

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