Molecular structures

We are studying metabolites, polysaccharides or proteins in isolated systems or directly in living organisms.

Examples of our research questions are:

• What are the metabolites involved in the pathogenicity of a fungus on a tree?
• What is the molecular basis behind biomolecular recognition ?
• How can both high and low abundance proteins be identified in a biological sample?

The central tools used in our research include NMR spectroscopy, mass spectrometry, X-ray crystallography and chromatography. One of our NMR instrument is equipped with a HR-MAS NMR probe allowing identifying and quantifying metabolites in living cells, tissues and plants.

Research areas

• Structural studies of polysaccharides
• Biomolecular interactions
• Development of NMR methods to study biomolecular structures, metabolites in living organisms
• Studies of secondary metabolites from bacteria, fungi and plants, for example with the aim to find new antibiotic compounds in microorganisms.
• Development of computational methods for accurate protein identification