Members of CRU

Members are listed alphabetically with name, title and affiliation. For PhD students, project title and supervisor is presented. For PhDs, current research activities and selected publications are given. For email address, please click on respective name.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Å Ä Ö

Agenäs, Sigrid; PhD, Assoc prof
Dept. of Animal Nutrition and Management, SLU, Uppsala
Keywords: Lactation physiology

Algers, Bo; Professor
Dept. of Animal Environment and Health, SLU, Skara
Keywords: Endocrinology and genetics in domestic animals.

Andersson, Leif; PhD, Professor
Dept. of Animal Breeding and Genetics, BMC, SLU, Uppsala
Keywords: Genetics in domestic animals.

Andersson, Marie; PhD-student
Dept. of Physiology and Developmental Biology, Environmental Toxicology, Uppsala University, Uppsala
Project title: Mechanism of excretion of the environmental adrenal toxicant MeSO2-DDE and related structures into breast milk
Principal supervisor: Ingvar Brandt
Keywords: Endocrinology, Multidrug Resistant Transporters

Axelsson, Jeanette; PhD
Dept. of Animal Breeding and Genetics, BMC, SLU, Uppsala
Keywords: Endocrine disruption, Japanese quail, sexual behavior, embryonic development, UV-filters.

Axnér, Eva; DVM, PhD, Professor, Dipl. ECAR
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Current research activities:
Feline sperm function, feline artificial insemination, lynx reproduction.
Publications:
1. Axnér E, Malmqvist M, Linde-Forsberg C, Rodrigues-Martinez H. Regional histology of the ductus epididymidis in the domestic cat. J Reprod Dev 1999, 45, 151-160.
2. Axnér E, Linde-Forsberg C, & Einarsson S. Morphology and motility of spermatozoa from different regions of the epididymal duct in the domestic cat. Theriogenology 1999, 52, 767-778.
3. Axnér E, Pukazhenthi BS, Wildt DE, Linde-Forsberg C, Spindler RE. Creatine phosphokinase in spermatozoa from different regions of the epididymis and correlation with sperm morphology in the domestic cat. Molecular Reproduction and Development 2002, 62, 265-270.
4. Chatdarong K, Kampa N, Axnér E, Linde-Forsberg C. Investigation of cervical patency and uterine appearance in domestic cats by fluoroscopy and scintigraphy. Reprod Dom Anim 2002, 37, 1-8.
5. Axnér E, Hermansson U, Linde-Forsberg C. The effect of Equex-STM paste and sperm morphology on post-thaw survival of cat epididymal spermatozoa. Anim Reprod Sci 2004, 84, 179.191.
6. Chatdarong K, Rungsipipat A, Axnér E, Linde-Forsberg C. Hysterographic appearance and uterine histology at different stages of the reproductive cycle and after progestagen treatment in the domestic cat. Theriogenology 2005, 64, 12-29.
Keywords: Reproduction, feline, canine, spermatozoa, artificial insemination.

Bannbers, Elin; PhD student
Dept. of Women's and Children's Health, Uppsala University Hospital, Uppsala
Project title: The effect of steroid hormones in the female brain during different reproductive states.
Principal supervisor: Prof. Inger Sundström Poromaa
Key words: Premenstrual dysphoric disorder, Functional magnetic resonance imaging, Response inhibition, Prepulse inhibition, Startle response

Berg, Cecilia; PhD, Associate professor
Dept. Environmental Toxicology, Uppsala University, Uppsala, Sweden.
Current research activities:
I am interested in sex differentiation and reproductive system development and how these processes are affected by exposure to chemicals. Transient exposure to chemicals during critical periods of embryo-foetal development can result in reproductive disorders and impaired fertility as the animal become adult. We investigate endocrine disruption, developmental and reproductive toxicity at several levels of biological organisation including molecular, physiological, and behavioural. One of the goals is to explore the African clawed frog (Xenopus tropicalis) as a vertebrate model to investigate developmental reproductive toxicity.
Selected publications:
1. Säfholm M, Norder, A, Fick J, Berg, C. (2012) Disrupted Oogenesis in the Frog Xenopus tropicalis After Exposure to Environmental Progestin Concentrations. Biology of Reproduction 86:126, 1-7.
2. Kvarnryd, M., Grabic, R., Brandt, I., Berg, C. (2011) Early life progestin exposure causes arrested oocyte development, oviductal agenesis and sterility in adult Xenopus tropicalis frogs, Aquatic Toxicology, 103:18–24. PubMed link
3. Gyllenhammar I, Holm L, Eklund R and Berg C (2009) Reproductive toxicity in Xenopus tropicalis after developmental exposure to environmental concentrations of ethynylestradiol. Aquatic Toxicology, 91: 171-178. PubMed link
4. Berg C, Blomqvist A, Holm L, Brandt I, Brunström B and Ridderstråle Y (2004) Embryonic exposure to oestrogen causes eggshell thinning and altered shell gland carbonic anhydrase expression in the domestic hen. Reproduction, 128: 455-461.
5. Berg C, Halldin K, Fridolfsson AK, Brandt I and Brunström B (1999) The Avian Egg as a Test System for Endocrine Disrupters: Effects of diethylstilbestrol and ethynylestradiol on sex organ development. Science of the Total Environment, 233: 57-66.
Keywords: Endocrine disruption, developmental reproductive toxicity, Müllerian duct differentiation, amphibian test system, gametogenesis.

Berglund, Britt; PhD, Professor
Dept. of Animal Breeding and Genetics, SLU, Uppsala
Current research activities:
My scientific field is in quantitative genetics and applied animal breeding. Specific area of research is in dairy cattle health and fertility traits, genetic and environmental variation, interrelationships between these traits and with productivity and longevity and their importance in a sustainable breeding programme.
Publications:
1. Berglund, B., Steinbock, L. & Elvander, M. 2003. Causes of stillbirth and time of death in Swedish Holstein calves post-mortem examined. Acta vet. scand. 44, 111-120.
2. Hagnestam, C., Emanuelson, U. & Berglund, B., 2007. Yield losses associated with clinical mastitis occurring in different weeks of lactation. J. Dairy Sci. 90, 2260-2270.
3. Odensten, M. O., Berglund, B., Persson Waller, K. & Holtenius, K. 2007. Metabolism and udder health at dry-off in cows of different breeds and production levels. J. Dairy Sci. 90, 1417-1428.
4. Petersson, K-J, Gustafsson, H., Strandberg, E. & Berglund, B. 2006. Atypical progesterone profiles and fertility in Swedish dairy cows. J. Dairy Sci., 89, 2529-2538.
5. Petersson, K-J, Berglund, B., Strandberg, E., Gustafsson, H., Flint, A.P.F., Wolliams, J.A. & Royal, M. 2007. Genetic analysis of postpartum measures of luteal activity in dairy cows. J. Dairy Sci. 90, 427-434.
Keywords: Dairy cows, genetic parameters, female fertility, stillbirths, calving difficulties.

Bergqvist, Ann-Sofi; DVM, PhD, Assoc prof, Dipl. ECAR
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Keywords: Glycosaminoglycans in dairy cattle reproduction.

Bergström, Ulrika; PhD, Researcher
Dept. of Environmental Toxicology, Evolutionary Biology Center, Uppsala University, Uppsala
Keywords: Developmental toxicology, bioactivation, genetics.

Björklund, Mats; Professor
Animal Ecology/Department of Ecology and Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala
Keywords: Speciation, reproductive physiology in birds.

Björkman, Camilla; FD, Professor
Dept. of Clinical Sciences, Division of Ruminant Medicine and Epidemiology, SLU, Uppsala
Current research activities:
My scientific field is veterinary infection diagnostics with focus on protozoan parasites. Specific area of research is diagnosis, epidemiology and control of protozoan parasites of domestic animals, e.g. N. caninum which is an important cause of abortion world-wide.
Publications:
1. Björkman, C., Näslund, K., Stenlund, S., Maley, S.W., Buxton, D. & Uggla, A. (1999) An IgG avidity ELISA to discriminate between recent and chronic Neospora caninum infection. Journal of Veterinary Diagnostic Investigation. 11, 41-44.
2. Björkman, C., Alenius, S., Emanuelson, U. & Uggla, A. (2000) Neospora caninum and bovine virus diarrhoea infections in Swedish dairy cows in relation to abortion. Veterinary Journal. 159, 201-206.
3. Frössling, J., Lindberg, A. & Björkman, C. (2006) Evaluation of an iscom ELISA used for detection of antibodies to Neospora caninum in bulk milk. Preventive Veterinary Medicine. 74, 120-129.
4. Loobuyck, M., Frössling, J., Lindberg, A & Björkman, C. (2009) Seroprevalence and spatial distribution of Neospora caninum in a population of beef cattle. Preventive Veterinary Medicine, 92, 116-122.
5. Williams, D.J.L., Hartley, C.S., Björkman, C. & Trees, A.J. (2009) Endogenous and exogenous transplacental transmission of Neospora caninum - how the route of transmission impacts on epidemiology and control of disease. Parasitology, 136, 1895-1900.
Keywords: Abortion, Neospora caninum, cattle, diagnosis, control

Brandt, Ingvar; Professor
Dept. of Environmental Toxicology, Evolutionary Biology Center, Uppsala University, Uppsala
Keywords:

Brodin, Thomas; M.D., PhD student
Dept. of Women's and Children's Health, Uppsala University, Uppsala, and
Carl von Linnékliniken, Uppsala Science Park, 751 83 Uppsala
Project title: Prognostic factors in assisted reproduction
Principal supervisor: Jan Holte
Keywords: Assisted reproduction, infertility, IVF/ICSI, IVF/ICSI outcome, ovarian reserve

Brunström Björn; PhD, Professor
Dept. of Environmental Toxicology, Uppsala University, Uppsala
Current research activities:
Effects of environmental contaminants in fish and birds. Special focus on interaction with nuclear receptors and endocrine disruption. Biomarkers in fish to study effects from pharmaceuticals in the environment.
Publications:
1. Brunström B, J. Axelsson, A Mattsson & K Halldin: Effects of estrogens on sex differentiation in Japanese quail and chicken. Gen Comp Endocrinol 2009, 163, 97-103.
2. Beijer K, A Abrahamson, B Brunström & I Brandt: CYP1A inhibition in fish gill filaments: A novel assay applied on pharmaceuticals and other chemicals. Aquat Toxicol 2010, 96, 145-150.
3. Mattsson A, JA Olsson & B Brunström: Activation of estrogen receptor alpha disrupts differentiation of the reproductive organs in chicken embryos. Gen Comp Endocrinol 2011, 172, 251-259.
4. Jönsson ME, BR Woodin, JJ Stegeman & B Brunström: Cytochrome P450 1 genes in birds: Evolutionary relationships and transcription profiles in chicken and Japanese quail embryos. PLoS ONE 2011, 6(12), e2857
5. Strömqvist M, JA Olsson, A Kärrman & B Brunström: Transcription of genes involved in fat metabolism in chicken embryos exposed to the peroxisome proliferator-activated receptor alpha (PPARα) agonist GW7647 or to perfluorooctane sulfonate (PFOS) or perfluorooctanoate (PFOA). Comp Biochem Physiol C Toxicol Pharmacol 2012, 156(1), 29-36.
Keywords: Reproductive and developmental toxicology, endocrine disrupters, pharmaceuticals, birds, fish

Båge, Renée; DVM, PhD, Assoc prof, Dipl. ECAR
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Current research activities:
Reproductive wastage after artificial insemination of Swedish dairy heifers and cows.
Effect of metabolic imbalance on the transcriptome profile of oocytes and early embryos in dairy cattle.
Molecular mechanisms involved in uterine response and resistance to infection in dairy cattle.
Reproductive performance and udder health in dairy cattle in sub-Saharan Africa.
Selected publications:
1. Nordéus K, Båge R, Gustafsson H, Humblot P, Söderquist L. The influence of oestrous substances on cyclicity and oestrous behaviour in dairy heifers. Acta Vet Scand. 2012 Apr 17;54:26.
2. Awasthi H, Saravia F, Rodríguez-Martínez H, Bage R. Do Cytoplasmic Lipid Droplets Accumulate in Immature Oocytes from Over-Conditioned Repeat Breeder Dairy Heifers? Reprod Domest Anim. 2010 Oct;45(5):e194-8. doi: 10.1111/j.1439-0531.2009.01514.x.
3. Petyim S, Bage R, Madej A, Larsson B. Ovum Pick-up in Dairy Heifers: Does it Affect Animal Well-being? Reprod Domest Anim. 2007 Dec;42(6):623-32.
4. Bergqvist AS, Killian G, Erikson D, Hoshino Y, Bage R, Sato E, Rodriguez-Martinez H. Detection of Fas ligand in the bovine oviduct. Anim Reprod Sci. 2005 Mar;86(1-2):71-88.
5. Bage R, Petyim S, Larsson B, Hallap T, Bergqvist AS, Gustafsson H, Rodriguez-Martinez H. Oocyte competence in repeat-breeder heifers: effects of an optimized ovum pick-up schedule on expression of oestrus, follicular development and fertility. Reprod Fertil Dev. 2003;15(1-2):115-23.
Keywords: Bovine gynecology and obstetrics, reproductive endocrinology, reproductive biotechnologies

Chalkias, Helena; PhD student
Dept. of Animal Breeding and Genetics, SLU, Uppsala
Keywords: Genetics, reproduction, sows, udder

Chanrot, Metasu; PhD student
Div. of Reproduction, Dept. of Clinical Sciences, SLU, Uppsala
Project title: Study of the effect of pathogens on bovine uterine tissue and possible differences between breeds in response to infectious challenges
Principal supervisor: Prof. Patrice Humblot
Keywords:

Dalin, Anne-Marie; DVM, PhD, Professor, Dipl. ECAR
Div. of Reproduction, Dept. of Clinical Sciences, SLU, Uppsala
Current research activities:
The sow endometrium during different stages of the oestrous cycle and during early pregnancy is studied. The qualitative and quantitative distribution by cells of the immune system is investigated including immunohistochemical studies on different cell markers such as CD2, CD4, CD8 and MHC classII expressing cells. Also e.g. ERa i relation to proliferative activities (marker Ki-67) is investigated.
Oestrous behaviour and ovarian activity in the mare: Mares that show strong or disturbed oestrous behaviour fail to perform at their best or become difficult to handle. Different models are used to study the oestrous behaviour in relation to ovarian activity and hormones, especially steroids.
Publications:
1. Tummaruk, P., N. Lundeheim, S. Einarsson and A.-M. Dalin, 2001. Factors influencing age at first mating in purebred Swedish Landrace and Swedish Yorkshire gilts. Anim. Rep. Sci., 63, 241 – 253.
2. Tummaruk, P., N. Lundeheim, S. Einarsson and A.-M. Dalin, 2001. Effect of birth litter size, birth parity number, growth rate, backfat thickness and age at first mating of gilts on their reproductive performance as sows. Anim. Rep. Sci. 66, 225 – 237.
3. Kaeoket, K., E. Persson and A.-M. Dalin, 2001. The sow endometrium at differerent stages of the oestrous cycle: Studies on morphological changes and infiltration by cells of the immune system. Anim. Rep. Sci. 65, 95 – 114.
4. Kaeoket, K., A.-M. Dalin, U. Magnusson and E. Persson, 2001. The sow endometrium at different stages of the oestrous cycle: studies on the distribution of CD2, CD4, CD8 and MHC class II expressing cells. Anim. Rep. Sci. 68, 99 – 109.
5. Dalin, A.-M., Æ Andresen and L. Malmgren, 2001. Immunisation against GnRH in mares; antibody titres, ovarian function, hormonal levels and oestrous behaviour. J. Vet. Med. A, accepted.
Keywords: Gynecology, endocrinology, histology, horse, swine

Dencker, Lennart; DVM, Professor, Dean
Dept. of Pharmaceutical Biosciences, BMC, Uppsala University, Uppsala
Keywords: Embryology, teratology, reproductive and developmental toxicology, toxicogenomics, proteomics.

Einarsson, Stig G; DVM, PhD, Professor emeritus, Dipl. ECAR
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Publications:
1. Suriyasomboon, A., Kunavongkrit, A,., Lundeheim, N. & Einarsson, S. Effect of temperature and humidity on reproductive performance of crossbred sows in Thailand. Theriogenology 2006, 65, 606-628.
2. Brandt, Y., Lang, A., Madej, A., Rodriguez-Martinez, H. & Einarsson S. Impact of ACTH administration on the oviductal sperm reservoir in sows: The local endocrine environment and distribution of spermatozoa. Anim. Reprod. Sci. 2006, 92, 107-122.
3. Brandt, Y., Lang, A., Madej, A., Rodriguez-Martinez, H. & Einarsson S. Impact of ACTH during oestrus on the ultrastructure of the spermatozoa and their environment in the tubal reservoir of the postovulatory sow. Anim. Reprod. Sci. 2006, 93, 231-245.
4. Brandt, Y., Lundeheim, N., Madej, A., Rodriguez-Martinez, H. & Einarsson, S. Effects of ACTH injections during estrus on concentrations and patterns of progesterone, estradiol, LH, and inhibin α and time of ovulation in the sow. Domestic Animal Endocrinology 2007, 32, 122-137.
5. Einarsson, S., Ljung, A., Brandt, Y., Häger, M. & Madej, A. Impact of exogenous ACTH during pro-oestrus on endocrine profile and oestrous cycle characteristics in sows. Reprod. Dom. Anim. 2007, 42, 100-104.
Keywords: Andrology, gynaecology, domestic animals especially pig, stress.

Ekman, Elisabet; DVM, MSc, PhD
Division of Pathology, Pharmacology and Toxicology, Dept. of Biomedical Sciences and Veterinary Public Health, SLU, Uppsala
Current research activities:
Evaluation of gonad morphology in small laboratory fish (zebrafish, Japanese medaka and fathead minnow).
Publications:
1. Ekman, E., Börjeson, H. & Johansson, N. (1999) Isolation of Flavobacterium psychrophilum from Baltic salmon Salmo salar brood fish and their offspring. Diseases of Aquatic Organisms, 37, 159-163.
2. Ekman, E., Åkerman, G., Balk, L. & Norrgren, L. (2003) Nanoinjection as a tool to mimic vertical transmission of Flavobacterium psychrophilum in rainbow trout Oncorhynchus mykiss. Diseases of Aquatic Organisms 55, 85-92.
3. Ekman, E., Norrgren, L. (2003) Pathology and immunohistochemistry in experimental infection with Flavobacterium psychrophilum in three species of salmonids. Journal of Fish Diseases 26, 529-538.
4. Ekman, E., Åkerman, G., Balk, L. & Norrgren, L. (2004) Impact of PCB on resistance to Flavobacterium psychrophilum after experimental infection of rainbow trout Oncorhynchus mykiss eggs by nanoinjection, Diseases of Aquatic Organisms 60, 31-39.
5. Blom, A., Ekman, E., Johannisson, A., Norrgren, L. & Pesonen, M, (1998), Effects of Xenoestrogenic Pollutants on the Proliferation of a Human Breast Cancer Cell Line (MCF-7). Archives of Environmental Contamination and Toxicology 34, 306-310.
Keywords: fish, endocrine disruption, infections diseases, Flavobacterium psychrophilum, morphology.

Ekstedt, Elisabeth; Vet. Med. Lic., Junior lecturer, PhD
Dept. of Anatomy, Physiology and Biochemistry, SLU, Uppsala
Keywords: Gynecology, andrology, endocrinology and reproductive technology in domestic animals.

Engblom, Linda; MSc, PhD
Dept. of Animal Breeding and Genetics, SLU, Funbo-Lövsta, Uppsala
Keywords: Nutrition, genetics, reproduction, infections in domestic animals.

Eriksson, Olle; MD, PhD
Dept. of Women's and Children's Health, Obstetrics and Gynecology, Uppsala University, Uppsala
Keywords:

Eriksson, Susanne; PhD
Dept. of Animal Breeding and Genetics, SLU, Uppsala
Current research activities: Estimation of variance components and genetic trends for female fertility and other traits in Swedish red cattle (SRB). Starting a new project about genetic and phenotypic analysis of field data including mating/artificial insemination and foaling records for Swedish warmblood riding horses and standardbred trotters. Also involved in a research project about genetic background of cryptorchidism in horses.
Publications:
1. Hansen Axelsson, H., Johansson, K., Eriksson, S., Petersson, K-J., Rydhmer, L., Philipsson, J. 2011. Selection of bull dams for production and functional traits in an open nucleus herd J. Dairy Sci. 94:2592–2600
2. Mikko, S., Andersson, L., Eriksson, S., Axelsson, J., Lindgren, G. 2010. Genomic tools and strategies for studying hereditary conditions in horses. Proc. 9th World Congress on Genetics Applied to Livestock Production. CD-ROM comm. no 898, 7pp. Aug 1-6, Leipzig, Germany.
3. Eriksson, S., Häggström, M., Stålhammar, S. 2007. Genetic analysis of superovulatory response in Swedish Red and Swedish Holstein heifers. The European Association of Animal Production, Dublin, Ireland.
4. Eriksson, S., Näsholm, A., Johansson, K. & Philipsson, J. 2004. Genetic relationships between calving and carcass traits for Charolais and Hereford cattle in Sweden. J. Anim. Sci. 82, 2269-2276.
5. Eriksson, S., Näsholm, A., Johansson, K. & Philipsson, J. 2004. Genetic parameters for calving difficulty, stillbirth and birth weight for Hereford and Charolais at first and later parities. J. Anim. Sci. 82, 375-383.
Keywords: genetic parameters, fertility, dairy cattle, horses, cryptorchidism.

Eriksson, Ulf; PhD, Professor
Dept. of Medical Cell Biology, Uppsala University
Keywords: Endocrinology, genetics and toxicology in human and rodents.

Forsberg, Mats; PhD, Professor emeritus, Dipl. ECAR
Dept. of Clinical Sciences, SLU, Uppsala
Keywords: Gynecology, andrology and endocrinology in domestic animals and other species.

Friberg, Urban; MSc, PhD
Dept. of Animal Ecology, Evolutionary Biology Centre, Uppsala University, Uppsala
Keywords: Sexual conflict, sexual selection, sperm competition, female choice

Grandinson, Katja; MSc, PhD
Dept. of Animal Breeding and Genetics, SLU, Funbo-Lövsta, Uppsala
Keywords: Sows, maternal behaviour, piglet mortality, heritability, genetic correlations.

Gustafsson, Hans; DVM, PhD, Professor, Dipl. ECAR
Dept. of Clinical Sciences, Division of Reproduction, SLU/ Swedish Dairy Association, Uppsala
Current research activities:
Reproductive herd health for dairy cows: The main goal for the dairy farmer is to get one living calf from each cow per year. Very few farmers succeed due to reproductive losses e.g. uterine disorders, ovarian disorders, embryonic death, abortions and stillbirths. My research area is focused on factors causing reproductive losses in dairy herds. The ultimate goal is to define and risk factors for reproductive disturbances and by e.g. reproductive herd health programs inhibit the risk factors and prevent reproductive diseases.
Publications:
1. Ratnayake, G, Berglund, B, Bertilsson, J., Forsberg, M. & Gustafsson, H. Fertility in dairy cows managed for calving intervals of 12,15 and 18 months. Acta vet. Scand., 1998, 39, 215-228.
2. Båge, R., Forsberg, M., Gustafsson, H., Larsson, B. & Rodriguez-Martinez, H. Effect of ACTH-challenge on progesterone and cortisol levels in ovariectomized repeat breeder heifers. Anim. Reprod. Sci., 2000, 63, 65-76.
3. Kask, K, Gustafsson, H, Gunnarsson, A & Kindahl, H Induction of parturition with prostaglandin F2a as a possible model to study impaired reproductiove performance in the dairy cow. Anim. Reprod. Sci., 2000, 59, 129-139.
4. Königsson, K., Gustafsson, H., Gunnarsson, A. & Kindahl, H. Clinical and bacteriological aspects on the use of tetracycline and flunixin in primiparous cows with induced retained placenta and post partal endometritis. Reprod. Dom. Anim. 2001, 36, 247-256.
5. Gustafsson, H., Larsson, B., Shamsuddin, M., Jaakma, U. & Emanuelson, U. Factors affecting the survival of frozen thawed bovine in vitro produced blastocysts. Asian-Australasian J. of Anim. Sci., 2001, 14, 7-12.
Keywords: Gynecology, endocrinology and reproductive technology in domestic animals.

Gustavsson, Ingemar; DVM, PhD, FK, Professor emeritus
Dept. of Animal Breeding and Genetics, SLU, Uppsala
Keywords: Genetics, reproductive technology and andrology in domestic animals.

Hagnestam Nielsen, Christel; Msc Agr, PhD
Dept. of Clinical Sciences, SLU, Uppsala
Key words: Dairy cows, female fertility, economics of health disturbances.

Hansen, Helen; PhD student
Dept. of Animal Breeding and Genetics, SLU, Uppsala
Keywords: reproduction of domestic animals, embryo technology, reproductive technology, fertility

Hanson, Ulf; MD, PhD, Assoc. Professor
Head of Dept. of Women’s and Children’s Health, Obstetric and Gynecology, Uppsala University, Uppsala
Current research activities:
I am working with research regarding Type-1-diabetes and preeclampsia, fetal growth. Screening for gestational diabetes.
Keywords: Diabetes, preeclampsia, gestational diabetes, screening, feto-maternal medicine.

Hallberg, Gunilla; MD, PhD student
Dept. of Women's and Children's Health, Obstetrics and Gynecology, Uppsala University, Uppsala
Keywords:

Hedberg, Ylva; DVM, PhD
UDS, SLU, Uppsala
Keywords: oestrous behaviour; adrenal hormones; mare

Hellgren, Charlotte; PhD student
Dept. of Women's and Children's Health, Uppsala University, Uppsala
Project title: Stress systems reactivity during pregnancy
Principal supervisor: Inger Sundström Poromaa
Keywords: pregnancy; autonomous nervous system; startle reflex; neurosteroids; cortisol

Hellmén, Eva; DVM, Professor, Dipl ECVP
Dept. of Anatomy, Physiology and Biochemistry, SLU, Uppsala
Current research activities:
The mammary glands are unique in the way that they are not mature at birth but not until puberty or even not until after a full term pregnancy. This means that genes that in other organs of the body only are expressed during the embryogenesis can be studied. The knowledge about stem cells in the mammary glands has increased the past decade but their role in tumorigenesis is not fully understood. Canine mammary tumours are frequent and have a large phenotypic plasticity compared to other species. Our research is focused on the different types of mammary tumours that appear and, although carcinomas, which originate from epithelial cells, dominate, sarcomas and mixed tumours also appear and the origin of the latter types is unknown. The aim of our research is to delineate how the different types of mammary tumours are formed and the end is to prevent their genesis.
Selected publications:
1. Ferletta M, Grawé J, Hellmén E. 2011, Canine mammary tumours contain cancer stem-like cells and form spheroids with an embryonic stem cell signature. Int J Dev Biol. 55(7-9):791-799.
2. Wensman H, Göransson H, Leuchowius KJ, Strömberg S, Pontén F, Isaksson A, Rutteman GR, Heldin NE, Pejler G, Hellmén E. 2009, Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas. Breast Cancer Res Treat. 118(2):333-43. Epub 2008 Dec 2.
3. Wensman H, Heldin NE, Pejler G, Hellmén E. 2009, Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors. PLoS One 22;4(9):e7133.
4. Wensman H, Flama V, Pejler G, Hellmén E. 2008, Plasticity of cloned canine mammary spindle cell tumor, osteosarcoma and carcinoma cells. Vet Pathol. 45(6):803-815.
5. Hellmén E, Moller M, Blankenstein MA, Andersson L, Westermark B. 2000, Expression of different phenotypes in cell lines from canine mammary spindle-cell tumours and osteosarcomas indicating a pluripotent mammary stem cell origin. Breast Cancer Res Treat. 61(3):197-210.
Keywords: mammary tumour, dog, canine, origin

Helmestam, Malin; PhD student
Dept. of Women's and Children's Health, Obstetrics and Gynecology, Uppsala University, Uppsala
Project title: Effects of some endocrine disruptors on Human Endometrial Endothelial cells.
Principal supervisor: Prof. Matts Olovsson.
Keywords: Angiogenesis, Endometrium, Human, Endothelial cells, Endocrine Disruptors

Hjernquist Mårten; PhD student
Dept of Animal Ecology/Department of Ecology and Evolution, Evolutionary Biology Centre, Uppsala University Uppsala
Project title: Evolution by environment interactions in the Collared Flycatcher.
Principal supervisor: Professor Lars Gustafsson
Keywords: Animal Ecology, Evolutionary Biology, Reproductive Biology.

Holm, Lena; PhD, Assoc. Prof.
Dept. of Anatomy, Physiology and Biochemistry, SLU, Uppsala
Current research activities:
Ongoing projects: I). Effects of phytoestrogen supplementation on eggshell formation and bone strength in laying hens. II). Analysis of male reproductive tract morphology in reproductive toxicology.
Publications:
1. Holm, L. Blomqvist, A. Brandt, I. Brunström, B. Ridderstråle, Y & Berg C. 2006 Embry-onic exposure to o,p´-DDT causes eggshell thinning and altered shell gland carbonic anhydrase expression in the domestic hen. ET & C, 25: 2787-2793 *
2. Jönsson, L & Holm, L. 2010 Effects of toxic and non-toxic Blue mussel meal on health and product quality of laying hens. J Anim Phys Anim Nutr 94: 405-412
3. Kalmendahl, R. Elwinger, K. Holm, L & Tauson, R. 2011. High-fibre sunflower cake affects small intestinal digestion and health in broiler chickens. Br Poult Sci, 52:86-96
4. Österström, O. Holm, L. Lilja, C. 2012 Calcium mobilization from the avian eggshell during embryonic development. Anim Biol. DOI 10.116315707563-00002392
5. Wistedt, A. Ridderstråle, Y. Wall, H. Holm, L. 2012 Effects of phytoestrogen supplemen-tation in the feed to laying hens at the end of the laying period. Anim Reprod Sci. 2012 Jun 30. [Epub ahead of print]
Keywords: Domestic hen, carbonic anhydrase, endocrine disruption, shell formation, testis.

Holte, Jan; MD, PhD, Senior Consultant, Chairman of the CRU board
Carl von Linné Clinic, Uppsala,
Current research activities:
Mainly in two fields: Polycystic Ovary Syndrome, specifically its association with metabolic aberrations and ovarian reserve, and prediction models in IVF. In collaboration with Uppsala Clinical Research Centre (UCR) the team at Carl von Linné Clinic is performing extensive prospective studies on factors determining outcome at IVF/ICSI, with the specific purpose to construct prediction models to optimize single embryo transfer strategies.
Selected publications:
Holte J, Brodin T, Berglund L, Hadziosmanovic N, Olovsson M, Bergh T 2011 Antral follicle counts are strongly associated with live-birth rates after assisted reproduction, with superior treatment outcome in women with polycystic ovaries. Fertil Steril 96:594-599.
Brodin T, Bergh T, Berglund L, Hadziosmanovic N, Holte J 2008 Menstrual cycle length is an age-independent marker of female fertility: results from 6271 treatment cycles of in vitro fertilization. Fertil Steril 90:1656-1661.
Holte J, Berglund L, Milton K, Garello C, Gennarelli G, Revelli A, Bergh T 2007 Construction of an evidence-based integrated morphology cleavage embryo score for implantationpotential of embryos scored and transferred on day 2 after oocyte retrieval. Hum Reprod 22:548-557.
Holte J, Gennarelli G, Wide L, Lithell H, Berne C 1998 High prevalence of polycystic ovaries and associated clinical, endocrine, and metabolic features in women with previous gestational diabetes mellitus. J Clin Endocrinol Metab 83:1143-1150.
Holte J, Bergh T, Berne C, Berglund L, Lithell H 1994 Enhanced early insulin response to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance. J Clin Endocrinol Metab 78:1052-1058
Keywords: Obstetrics, gynaecology, IVF, PCOS

Holtenius, Kjell; PhD, Professor
Dept. Animal Nutrition and Management, Kungsangen Research Center, SLU, Uppsala
Keywords: Endocrinology and nutrition in domestic animals.

Hreinsson, Julius; PhD, Laboratory Director
Reproduction Centre, Uppsala University Hospital
Keywords:

Humblot, Patrice; DVM, PhD, Professor
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Current research activities:
Molecular biology is used to analyse reproductive response in various reproductive tissues (oocytes and follicular cells, endometrium, embryos) when animals or cells are exposed to metabolic imbalance or to pathogens. A special focus is given to epigenetic basic status and changes when studying the impact of those factors. In vitro models or in vivo models based on comparison between individuals expressing different phenotypes or different breeds are used to detect potential phenotypic or molecular markers of reproductive robustness which may be used in selection or to optimize therapeutic strategies.
Keywords: Phenotyping of reproduction, reproductive robustness, metabolic imbalance and reproduction, host pathogen interactions in reproductive tissues, epigenetics and reproduction.

Höglund, Odd; DVM, PhD
Dept of Clinical Sciences, SLU, Uppsala
Keywords: Surgery, reproductive surgery, gynaecology, dog, cat

Immler, Simone; PhD
Evolutionary Biology, Dept of Ecology and Evolution, EBC, Uppsala University, Uppsala.
Keywords: Evolutionary biology, postcopulatory sexual selection, haploid selection

Jansson, Erika; PhD-student
Dept. of Physiology and Developmental Biology, Environmental Toxicology, Uppsala University, Uppsala Project title: Amphibians as a model to investigate developmental and reproductive toxicity.
Principal supervisor: Assoc. Prof. Cecilia Berg.
Keywords: Pharmaceuticals, amphibians, endocrine disruption, reproductive toxicity

Jitpean, Supranee; PhD student
Dept of Clinical Sciences, SLU, Uppsala
Project title: Pyometra in dogs.
Principal supervisor: Assoc Prof Ragnvi Hagman
Keywords: Pyometra, bitches, surgery, complications, morphological studies

Johannisson, Anders; PhD, Prof
Dept. of Anatomy, Physiology and Biochemistry, SLU, Uppsala

Junus, Katja; PhD student
Dept. of Women's and Children's Health, Uppsala University Hospital, Uppsala
Project title: Pathophysiological differences in early- and late-onset preeclampsia
Principal supervisor: Prof. Matts Olovsson
Key words: Early- and late-onset preeclampsia, placenta, microarray, NT-proBNP, micro-particles

Jönsson, Maria; PhD
Dept. of Environmental Toxicology, Evolutionary Biology Centre, Uppsala University, Uppsala.
Current research activities:
The CYP1 family and AhR-mediated toxicity.
Biomarkers for CYP1A induction and Ah-receptor mediated toxicity in fish.
Publications:
1. Andersson C, Abrahamson A, Brandt I, Jönsson M, Otte J, Örberg J and Brunström B (2006) Gill filament EROD activity in the three-spined stickleback (Gasterosteus aculeatus L.) as a biomarker for exposure to Ah receptor agonists in the water. Dioxin 2006, Oslo, Norway.
Keywords:

Kindahl, Hans; DVM, PhD, Professor emeritus, Dipl. ECAR
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Current research activities:
Mainly interested in prostaglandin biosynthesis during different physiological (luteolysis, parturition, uterine involution) or pathological (endotoxaemia, fasting, stress, abortion, premature parturition and stillbirth, postpartum endometritis) events. These studies are done on a comparative basis including several domestic species. A strong focus today in the research activities towards exaggerated sexual behaviour and endometritis in mares. Intensive studies concerning use of anti-inflammatory drugs (NSAID:s) to control prostaglandin biosynthesis in eg. luteolysis and inflammatory processes. These studies include clinical changes, prostaglandin formation and pharmacokinetic studies of the drugs. Have a long tradition to analyse prostaglandin metabolites using RIA:s.
Publications:
1. Nikolakopoulos, E., Kindahl, H., Gilbert, C.L., Goode, J. & Watson, E.D. Oxytocin and PGF2a release around teasing, natural service and associated events in the mare. Anim. Repro. Sci. 63 (2000) 89-99.
2. Kindahl, H., Odensvik, K., Hansen, B. & Daels, P.F. Changes in PGF2a secretion during prolonged luteal phase in mares. J. Reprod. Fert., Suppl. 56 (2000) 305-315.
3. Kask, K., Gustafsson, H. Gunnarsson, A. & Kindahl, H. Induction of parturition with prostaglandin F2a as a possible model to study impaired reproductive performance in the dairy cow. Anim. Reprod. Sci. 59 (2000) 129-139.
4. Kornmatitsuk, B., Königsson, K., Kindahl, H., Gustafsson, H., Forsberg, M. & Madej, A. Clinical signs and hormonal changes in dairy heifers after PGF2a-induced parturition. J. Vet. Med. 47 (2000) 395-410.
5. Königsson, K., Gustafsson, H., Gunnarsson, A. & Kindahl, H. Clinical and bacteriological aspects on the use of tetracycline and flunixin in primiparous cows with induced retained placenta and post partal-endometritis. Reprod. Dom. Anim. 36 (2001) 247-256. Keywords: Reproductive endocrinology, reproductive disorders, prostaglandin biosynthesis, inflammation, anti-inflammatory drugs.

Kirilovas, Dmitrijus; MD, PhD student
Dept. of Women's & Children's Health, Obstetrics & Gynecology, Uppsala University, Uppsala
Supervisor: Assoc. Prof. Tord Naessen
Keywords: Aromatase activity, paracrine regulation, polycystic ovary syndrome, positron emission tomography, rat.

Kronqvist, Cecilia; PhD
Dept. Animal Nutrition and Management, Kungsangen Research Center, SLU, Uppsala.
Project title: Minerals to dairy cows with focus on calcium and magnesium balance.
Supervisor: Prof. Kjell Holtenius.
Keywords: Calcium, magnesium, milk fever, dry cow feeding, dairy cows.

Kunovac Kallak, Theodora; PhD student
Dept. of Women's and Children's Health, Uppsala University, Uppsala
Project title: Hormonal regulation in vaginal mucosa in women undergoing anti-hormonal treatment against breast cancer and in postmenopausal women.
Principle supervisor: Anneli Stavreus Evers and Inger Sundström Poromaa
Key words: Vagina, hormonal regulation, anti-hormonal treatment, urogenital discomforts and estrogens.

Lagerkvist, Gabrielle; PhD, Researcher
Dept. of Animal Breeding and Genetics, SLU, Uppsala
Keywords: Genetics and endocrinology in human and domestic animals.

Lagerstedt, Anne-Sofie; DVM, PhD, Professor
Dept. of Clinical Sciences, SLU, Uppsala
Keywords: Gynecology, obstetrics and infections in dogs and cats.

Laskowski, Denise; DVM, PhD student
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Project title: Does induction of metabolic imbalance change the transcriptomic profiling of oocytes and early embryos in dairy cattle?.
Principal supervisor: Prof. Hans Gustafsson
Keywords: Reproduction, cattle, nutrition, insulin, embryo development, epigenetics

Lindahl, Elisabeth; DVM, PhD student
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Project title:Brucellosis and periurban dairy cows in Tajikistan
Keywords: Brucellosis, periurban farming, zoonoses, ruminants, Central Asia.

Lindahl, Johanna; DVM, PhD student
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Project title: Japanese Encephalitis Virus in Pigs in urban farming in the Mekong delta.
Principal supervisor: Prof. Ulf Magnusson
Keywords: Japanese encephalitis, peri-urban agriculture, virology, Vietnam, porcine reproduction.

Linde-Forsberg, Catharina; DVM, PhD, Professor emeritus, Dipl. ECAR
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Current research activities:
Reproductive patterns and disturbances in different dog breeds in Sweden.
AI in dogs and cats.
Sperm preservation, dog.
Chlamydia in dogs.
Comparison between dog and wolf concerning changes in exterior.
Publications:
1. Shahiduzzaman AK, Linde-Forsberg C. Induced immotility during long-term storage at +5 degrees C does not prolong survival of dog spermatozoa. Theriogenology. 2007 Aug 20; [Epub ahead of print]
2. Axner E, Linde Forsberg C. Sperm morphology in the domestic cat, and its relation with fertility: a retrospective study. Reprod Domest Anim. 2007 Jun;42(3):282-91.
3. Linde Forsberg C, Persson G. A survey of dystocia in the Boxer breed. Acta Vet Scand. 2007 Mar 21;49(1):8.
4. Ortega-Pacheco A, Segura-Correa JC, Jimenez-Coello M, Linde Forsberg C. Reproductive patterns and reproductive pathologies of stray bitches in the tropics. Theriogenology. 2007 Jan 15;67(2):382-90. Epub 2006 Sep 27.
5. Ortega-Pacheco A, Rodriguez-Buenfil JC, Segura-Correa JC, Bolio-Gonzalez ME, Jimenez-Coello M, Linde Forsberg C. Pathological conditions of the reproductive organs of male stray dogs in the tropics: prevalence, risk factors, morphological findings and testosterone concentrations. Reprod Domest Anim. 2006 Oct;41(5):429-37.
6. Chatdarong K, Ponglowhapan S, Karlsson A, Linde-Forsberg C. The effect of ACTH stimulation on cortisol and progesterone concentrations in intact and ovariohysterectomized domestic cats. Theriogenology. 2006 Oct;66(6-7):1482-7. Epub 2006 Mar 9.
Keywords: Small animal reproduction, artificial insemination, dog, cat, canine and feline semen preservation.

Lindgren, Karin; PhD student
Dept of womens' and childrens health, Uppsala Academic hospital, Uppsala
Project title: Infertility with focus on the underlying mechanisms, diagnosis and treatment
Principal supervisor: Assoc. Prof. Helena Åkerud
Keywords: Infertility, single nucleotide polymorphism, Histidine-rich glycoprotein, angiogenesis, implantation

Lomander, Hanna; PhD student
Section of Production Diseases, Dept of animal Environment and Health, 532 23 Skara
Project title: Effect of glucogenic supplementation in early lactation on reproduction, milk yield and metabolic status in Swedish dairy cows.
Principal supervisor: Jenny Frössling
Keywords: Dairy cow, endocrinology, nutrition, metabolic disease

Lundberg, Åsa; DVM, PhD student
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Project title: Genetic variation and spread of Staphylococcus aureus, Streptococcus dysgalactiae and Streptococcus uberis in mastitis in dairy cows
Principal supervisor: Karin Persson Waller
Keywords: Mastitis bacteriology, dairy cows

Lundeheim, Nils; PhD, Senior research officer
Dept. of Animal Breeding and Genetics, SLU, Funbo-Lövsta, Uppsala
Keywords: Genetics, gynecology and obstetrics in domestic animals.

Lundgren, Helena; MSc, PhD student
Dept. of Animal Breeding and Genetics, SLU, Uppsala
Keywords: Genetics, reproduction, sows, piglet growth.

Lundmark, Malin; PhD student
Dept. of Women's and Children's Health, UU, Uppsala
Project title: The effects of some hormones, chemicals and endocrine disruptors on human endometrial cells in vitro.
Principal supervisor: Matts Olovsson and Anneli Stavreus Evers.
Keywords: Endocrine disruptors, human reproduction.

Madej, Andrzej; MSc, PhD, Professor
Dept. of Anatomy, Physiology and Biochemistry, SLU, Uppsala
Publications:
1. Madej, A., Persson, E., Lundh, T. & Ridderstråle, Y. (2002) Thyroid gland function in ovariectomized ewes exposed to phytoestrogens. J. Chromatography B 777:281-287.
2. Polkowska, J., Ridderstråle, Y., Wankowska, M, Romanowicz, K., Misztal, T. & Madej, A. (2004) Effects of intracerebroventricular infusion of genistein on gonadotrophin subunit mRNA and immunoreactivity of gonadotrophins and oestrogen receptor-α in the pituitary cells of the anoestrous ewe. Journal of Chemical Neuroanatomy 28:217-224.
3. Madej, A., Lang, A., Brandt, Y., Kindahl, H., Madsen M.T & Einarsson S. (2005) Factors regulating ovarian function in pigs. Domest. Anim. Endocrinol. 29:347-361.
4. Gunnarsson, D, Selstam, G., Ridderstråle, Y., Holm, L., Ekstedt, E. & Madej, A. (2009) Effect of dietary supplement of phytoestrogens on steroid production, cAMP and thyroid hormones in male goat kids. Acta Vet. Scand. 51:51
5. Brandt, Y., Ljung, A., Lundeheim, N., Rodríguez-Martínez, H., Einarsson, S. & Madej, A. (2009) Effects of continuous elevated cortisol concentrations during oestrus on concentrations and patterns of progesterone, oestradiol and LH in the sow. Anim. Reprod. Sci. 110:172-185.
Keywords: Endocrinology, nutrition and toxicology in domestic animals and rodents.

Magnusson, Ulf; DVM, PhD, Professor, Dipl. ECAR
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Current research activities:
Reproduction and infections: Bacterial infections in reproductive organs such as the uterus and mammary gland are major obstacles in animal husbandry. Very often these infections are caused by commensal bacteria why we have focused on the body’s defence mechanisms, specifically the immune system. In the mare we study the uterus and in the sow the mammary gland. The aim of these studies are to provide a basis for better preventive and therapeutic measures for endometritis and mastitis. Also, currently we perform epidemiological studies of the bacterial zoonosis leptospiros among pigs in Vietnam.
Environmental reproductive toxicity: This is a new research field in which we study the effect of low doses of compounds present in the environment on the reproductive functions of pigs.
Publications:
1. Hormonal and immunological changes in blood and mammary secretion in the sow at parturition. Österlundh, I, Holst H, and Magnusson U, 1998. Theriogenology, 50:465-477.
2. A longitudinal study of lymphocyte subsets and MHC class II expressing cells in the mammary gland of sows. Magnusson U, 1999. Am J Vet Res, 60: 546-548.
3. Influence of age and parity of MHC class II, CD4 and CD8 expressing cells in the equine endometrium during estrus. Tunon AM, Rodriguez-Martinez H, Nummijärvi A, and Magnusson U, 1999. Am J Vet Res, 60: 1531-1536.
4. Prepubertal boars exposed to the endocrine disrupting chemical DEHP: Late effects on blood testosterone concentrations. Magnusson U, Hultén F, Norrgren L and Einarsson S, 2001, Abstract, BASE vol 5: 83-84.
5. Animal- and herd-level risk factors for leptospiral seropositivity among sows in the Mekong delta, Vietnam. Boqvist S, B.L. Chau, Gunnarsson A., Olsson Engvall E., Vågsholm I and Magnusson U, 2002. Preventive Veterinary Medicine, in press.
Keywords: Gynecology, endocrinology and infections in domestic animals.

Malmsten, Jonas; PhD student
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Project title: Reproduction in moose - basic physiology and impact of disease
Principal supervisor: Anne-Marie Dalin
Keywords: cervids, reproduction, physiology, pathogens, oestrus

Mattsson, Anna; PhD, Post doc
Dept. Environmental Toxicology, Uppsala University, Uppsala
Current research activities:
My research field is developmental toxicology and includes studies of how environmental chemicals may affect development of the reproductive system as well as studies of metabolic activation of pro-teratogenic chemicals. Present and previous model animals include quail, chicken, zebrafish and frogs.
Selected publications:
1. Mattsson, A., Ullerås, E., Patring, J. & Oskarsson, A. (2012) Albendazole causes stage-dependent developmental toxicity and is deactivated by a mammalian metabolization system in a modified zebrafish embryotoxicity test. Reprod. Toxicol., 34, 31-42.
2. Mattsson, A., Olsson, J.A. & Brunström, B. (2011) Activation of estrogen receptor alpha disrupts differentiation of the reproductive organs in chicken embryos. Gen. Comp. Endocrinol., 172, 251-259.
3. Norman Haldén, A., Arnoldsson, K., Haglund, P., Mattsson, A., Ullerås, E., Sturve, J. & Norrgren, L. (2011) Retention and maternal transfer of brominated dioxins in zebrafish (Danio rerio) and effects on reproduction, aryl hydrocarbon receptor-regulated genes, and ethoxyresorufin-O-deethylase (EROD) activity. Aquat. Toxicol., 102, 150-161.
4. Mattsson, A. & Brunström, B. (2010) Effects on differentiation of reproductive organs and sexual behaviour in Japanese quail by excessive embryonic ERalpha activation. Reprod. Fertil. Dev., 22, 416-425.
5. Mattsson, A., Mura, E., Brunström, B., Panzica, G. & Halldin, K. (2008) Selective activation of estrogen receptor alpha in Japanese quail embryos affects reproductive organ differentiation but not the male sexual behavior or the parvocellular vasotocin system. Gen. Comp. Endocrinol., 159, 150-157.
Keywords: Developmental toxicity, endocrine disruption, malformations, metabolic activation

Melin, Malin; PhD
Dept of Animal Breeding and Genetics, BMC, SLU, Uppsala
Keywords: Mammary tumors, genetic risk factors, dog

Murto, Tiina; Midwife,MSc, PhD student
Department of Women´s and Children's Health,Uppsala University
Project title: Relation between nutrition, health and unexplained infertility from a socio-economic perspective.
Principal supervisor: Assoc. Professor Anneli Stavreus-Evers
Keywords:Infertility, folate, reproduction, genetic polymorphisms, dietary supplement.

Möller, Björn; Biomedicine magister, PhD student
Dept. of Women's and Children's Health, Obstetrics and Gynecology, Uppsala University, Uppsala
Supervisor: Matts Olovsson
Keywords: Angiogenesis, endometrium, VEGF, VEGF receptors, contraception.

Ntallaris, Theodoros; DVM
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Keywords: Reproduction, cattle, reproductive biotechnologies, herd health

Neil, Maria; AgrD, Assoc. Professor
Dept. of Animal Nutrition and Management, SLU Funbo-Lövsta, Uppsala
Keywords: Nutrition in domestic animals.

Nordqvist, Sarah; MD, PhD student
Dept. of Women´s and Children's Health,Uppsala University
Project title: Histidine-rich glycoprotein and fertility
Principal supervisor: Helena Åkerud
Key words:IVF, fertility, angiogenesis, pregnancy, histidine-rich glycoprotein

Norman Haldén, Anna; PhD
Department of Biomedical Sciences and Veterinary Public Health, Division of Pathology, Pharmacology and Toxicology, SLU, Uppsala
Keywords: Reproduction, brominated flame retardants, endocrine disruptors, fish, gonad morphology

Norrgren, Leif; PhD, Professor
Department of Biomedical Sciences and Veterinary Public Health, Division of Pathology, Pharmacology and Toxicology, SLU, Uppsala
Current research activities:
We perform baseline studies on perch and roach in Swedish waters with a focus on gonad morphology, this in order to describe the cause to inadequate gonad maturation and intersex. In addition we are focusing on reproduction disorders in several Baltic Sea fish species, i.e. cod and salmon (M74 syndrome). Another important task is to develop test protocols for zebrafish including short-term and confirmatory tests which can be used to develop OECD guidelines. Recently we have started to work with amphibians, both native and exotic species. Major groups of chemicals which we are interested in includes musks, brominated flame retardants, PCBs and PAHs. We are also working with infectious diseases in salmonids (renibacteriosis and flavobacteriosis). For more information you can look at www.pat.slu.se (Aquatic ecotoxicology).
Publications:
1. Norrgren L, Amcoff , P, Börjeson H and Larsson P-O (1998) Reproduction disturbances in Baltic fish-A rewiev. American Fisheries Soc. 21:8-17.
2. Örn, S., Andersson, P., Förlin, L., Tysklind, M. and Norrgren, L (1998) The impact on reproduction of an orally administered mixture of selected PCBs in zebrafish (Danio rerio). Arch. Env. Con. Tox. 35,1, 52-57.
3. Norrgren L, Blom A, Andersson PL, Börjeson H, Larsson, DGJ and Olsson P-E (1999) Effects of potential xenoestrogens (DEHP, nonylphenol and PCB) on sexual differentiation in juvenile Atlantic salmon (Salmo salar). Aq. Ecosystem Health and Management, 2, 311-317.
4. Åkerblom N, Olsson, K., Berg, H., Andersson, P., Tysklind, M. Förlin, L. and Norrgren, L. (2000) Impact of polychlorinated naphthalenes (PCNs) in juvenile Baltic salmon, Salmo salar; Evaluation of estrogenic effects, development, and CYP1A induction. Arch. Envir. Con. Tox. 38 225-233.
5. Andersen L., Petersen G., Gessbo Å., Örn S., Holbech H., Bjerregaard P. and Norrgren L. (2001) Zebrafish (Danio rerio) and roach (Rutilus rutilus)-two species suitable for evaluating effects of endocrine disrupting chemicals? Aq. Ecosystem Health and Management in press.
Keywords: Reproduction, pollutants, endocrine disruptors, fish, amphibians.

Nyman, Sofia; PhD student
Department of Animal Breeding and Genetics, SLU, Uppsala
PhD project: Genetic and genomic variation in different fertility traits in dairy cows.
Principal supervisor: Britt Berglund
Keywords: Dairy cows, fertility, estrus strength, atypical progesterone profiles, genetic merit.

Näslund, Johanna; DVM, PhD student
Department of Biomedical Sciences and Veterinary Public Health, Division of Pathology, Pharmacology and Toxicology, SLU, Uppsala
PhD project: Reproductive health in coastal fish in the Baltic Sea.
Supervisor: Leif Norrgren
Keywords: Fish, pathology, endocrine disruption, environmental toxins, gonad morphology.

Oli Ullah, Mohammad; MSc student
SLU, Uppsala

Olovsson, Matts; MD, PhD, Professor
Dept. of Women’s and Children’s Health, Obstetrics & Gynecology, Uppsala University, Uppsala
Current research activities:
Endometrial angiogenesis (the formation of new blood vessels) is important for fertility and bleeding control. We study the expression of regulators of angiogenesis and blood vessel function in in serum, peritoneal fluid and tissue biopsies from normal and dysfunctional endometrium, endometriotic lesions and peritoneum.
Pre-eclampsia (PE) is studied in a new rat model developed by us and in humans. Oxidative stress is believed to be involved in the pathogenesis of PE and it has been shown that antioxidants like vitamin E can reduce the incidence of the disease. inhibitors of. The rat model is used to test hypothesis about the pathogenesis to PE and how the development of PE can be blocked.
We also study the relationship between uterine leiomyomas and endocrine disruptors (PCB, DDT and others, and, their metabolites) in the baltic seal and humans. We have found that leiomyomas occur quite frequently in seals in the baltic sea but is rare in the same species in the Atlantic sea. In vitro studies have pointed out some of the metabolites as strong stimulators of proliferation on uterine myocytes from seal. Human cells have not yet been tested.
Methods used are cell culturing, cell proliferation assays, immunohistochemistry, western blotting, etc.
Publications:
1. Möller,B., Lindblom,B., Rasmussen,C. and Olovsson,M. (2001) Localized expression of the angiogenic growth factors vascular endothelial growth factor (VEGF), fibroblast growth factor 2 (FGF-2), epidermal growth factor (EGF), and their receptors in normal human endometrium during the menstrual cycle. Mol. Hum. Reprod. Jan;7(1):65-72.
2. Xuxia,W., Blanck,A., Olovsson,M., Möller,B., Favini,R., and Lindblom,B. (2000) Apoptosis, cellular proliferation and expression of p53 in human uterine leiomyomas and myometrium during the menstrual cycle and after maenopause. Acta Obstet. Gynecol. Scand. 79(5):397-404.
3. M. Olovsson, M. Nordling, U. Ulmsten, B. Lindblom, A. Waldenström and G. Ronquist. (2000) Human uterine myocytes retain normal metabolic parameters for at least 14 days when cultured under anaerobic conditions. Gynecol. Obstet. Invest. 49(3): 165-169.
4. B.M. Bäcklin, L. Eriksson and M. Olovsson. Histology of uterine leiomyoma and occurrence in relation to reproductive activity in the Baltic grey seal (Halichoerus grypus). Accepted for publication in Veterinary Pathology.
Keywords: Human, endometrium, angiogenesis, pre-eclampsia, uterine leiomyoma.

Oskarsson, Agneta; PhD, Professor
Dept of Biomedical Sciences and Veterinary Public Health. Div of Pathology, Pharmacology and Toxicology, SLU, Uppsala
Current research activities:
Endocrine disruption via effects on steroidogenesis.
Developmental effects after perinatal exposure of environmental toxicants.
Active transport of xenobiotics into milk.
Publications:
1. Ohlsson, Å., Ullerås, E. and Oskarsson, A.: A biphasic effect of the fungicide prochloraz on aldosterone, but not cortisol, secretion in human adrenal H295R cells – underlying mechanisms. Toxicol. Lett., 191, 174-180, 2009.
2. Ohlsson, Å., Cedergreen, N., Ullerås, E. and Oskarsson, A.: Mixture effects of dietary flavonoids on steroid hormone synthesis in the human adrenocortical H295R cell line. Food Chem. Toxicol., 48, 3194-3200, 2010.
3. Öhrvik, H., Ullerås, E., Oskarsson, A. and Tallkvist, J.: Effects of cadmium on calcium transporter SPCA, calcium homeostasis and β-casein expression in the murine mammary epithelium. Toxicol. Lett., 201, 80-85, 2011.
4. Carlsson, G., Patring, J., Ullerås, E. and Oskarsson, A.: Developmental toxicity of albendazole and its three main metabolites in zebrafish embryos. Reprod. Toxicol., 32, 129-137, 2011.
5. Mattsson, A., Ullerås, E., Patring, J. and Oskarsson, A.: Albendazole shows stage-dependent developmental toxicity and is deactivated by a mammalian metabolization system in a modified zebrafish embryo toxicity test. Reprod. Toxicol., 34, 31-42, 2012.
Keywords: Toxicology, food safety, milk, transporters, developmental and reproductive toxicology, steroidogenesis

Osbjer, Kristina; DVM, MSc, PhD student
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Project title: Zoonoses in rural Cambodia
Principal supervisor: Prof. Ulf Magnusson
Keywords: Zoonoses, influenza, Campylobacter, developing countries and (veterinary) public health.

Persson, Elisabeth; DVM, PhD, Assoc. Professor
Dept. of Anatomy, Physiology and Biochemistry, SLU, Uppsala
Keywords: Female reproduction, endometrium, placenta, morphology, immunohistochemistry

Persson, Sara; DVM, PhD student
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Project title: The mink as sentinel species for environmental monitoring of reproductive toxicology.
Principal supervisor: Prof. Ulf Magnusson
Keywords: Reproductive and developmental toxicology, free ranging (and farmed) mink.

Petersson, Karl-Johan; PhD
Dept. of Animal Breeding and Genetics, SLU, Uppsala, Sweden
Publications:
1. Petersson, K.-J., Kolmodin, R. & Strandberg, E. 2005. Genotype by environment interaction for length of productive life in Swedish Red and White dairy cattle. Acta Agriculturae Scandinavica, Section A Animal Science, 55, 9-15.
2. Petersson, K.-J., Strandberg, E., Gustafsson, H. & Berglund, B. 2006. Environmental effects on progesterone profile measures of dairy cow fertility. Animal Reproduction Science 91, 201-214.
3. Petersson, K.-J., Gustafsson, H., Strandberg, E. & Berglund B. 2006. Atypical progesterone profiles and fertility in Swedish dairy cows. Journal of Dairy Science 89, 2529-2538.
4. Petersson, K.-J., Berglund, B., Strandberg, E., Gustafsson, H., Flint, A.P.F., Woolliams, J.A. & Royal, M.D. 2007. Genetic analysis of postpartum measures of luteal activity in dairy cows. Journal of Dairy Science 90, 427-434.
Keywords:

Proos, Lemm; DMSc
Dept. of Women’s and Children’s Health, Pediatrics, Uppsala University, Uppsala
Keywords:

Qvarnström, Anna; PhD, Assoc. Professor
Dept. of Ecology and Evolution, Section of Animal Ecology, UU, Uppsala, Sweden
Current research activities:
I study the mechanisms of speciation (i.e. how reproductive isolation evolves) by investigating causes and consequences of gene flow between two naturally hybridizing species of birds (pied and collared flycatchers).
Publications:
1. Qvarnström A., Pärt, T. and Sheldon BC.2000. Adaptive plasticity in mate preferences linked to differences in reproductive effort, Nature 405, 344-347.
2. Qvarnström A. and Price, T. 2001 Maternal effects, paternal effects, and sexual selection, Trend. Ecol. Evol, 16, 95-100.
3. Price, TD, Qvarnström, A and Irwin, DE. 2003. The role of phenotypic plasticity in driving genetic evolution, Proc. R. Soc. Lond. B, 270, 1433-1440.
4. Qvarnström, A, Blomgren, V, Wiley, C and Svedin, N. 2004. Female collared flycatchers learn to prefer males with an artificial novel ornament. Behav, Ecol15, 343-348.
5. Qvarnström, A, Svedin, N, Wiley, C, Veen, T. and Gustafsson, L. 2005. Cross-fostering reveals seasonal changes in the relative fitness of two competing species of flycatchers. Biol. Letters,1, 68-71.
Keywords: Reproductive isolation, speciation, sexual selection, life-history evolution, mate choice.

Ridderstråle, Yvonne; PhD, Professor
Dept. of Anatomy, Physiology and Biochemistry, SLU, Uppsala
Current research activities:
Morphological methods combining immunohistochemistry, histochemistry, x-ray microanalysis, image analysis, light and electron microscopy are used in the following projects: a) Sperm motility and sperm storage in birds, b) Effects of embryonic exposure to estrogens on carbonic anhydrase and bird reproduction. c) Effects of phytoestrogens on sheep and goat fertility.
Publications:
1. Holm, L. & Ridderstråle, Y. (1998) Localisation of carbonic anhydrase in the sperm storing regions of the turkey and quail oviduct. Histochem. J. 30: 481-488.
2. Holm, L., Ekwall, H., Wishart, G.J. & Ridderstråle, Y. (2000) Localisation of calcium and zinc in the sperm storage tubules of chicken, quail and turkey using x-ray microanalysis. J. Reprod. Fertil. 118:331-336.
3. Holm L., Ruziwa S. D., Dantzer, V. & Ridderstråle Y. (2000) Carbonic anhydrase in the utero-vaginal junction of immature and mature ostriches. Br. Poult. Sci. 41:244-249.
4. Holm, L., Berg, C., Brunström,B., Ridderstråle,Y. & Brandt, I. (2001). Disrupted carbonic anhydrase distribution in the avian shell gland following in ovo exposure to estrogen. Arch Toxicol 75:362-368.
Keywords: Carbonic anhydrase, endocrine disruption, shell formation, firds, phytoestrogens.

Risberg, Anitha; PhD student
Dept. of Medical Cell Biology, Uppsala University, Uppsala
Principal supervisor: Prof. Mats Sjöquist; Inst. of Cellbiology, integrative physiology, BMC, UU.
Keywords: hormonal changes, pregnancy, water balance, salt balance, blood pressure.

Ronquist, Göran; PhD
Dept of Medical Sciences, Biochemial structure and function, Uppsala Universitet, Uppsala.
Current research activities:
Prostasomes are membrane-surrounded microvesicles (mean diameter 150 nm, range 40-490 nm) secreted from epithelial cells of the prostate gland. Prostasomes constitute an important part of the prostatic fluid and thereby being a prominent component of the seminal fluid. They promote sperm forward motility and protect sperm cells from attacks from the female immune system and exert complement system-inhibitory activities thus supporting the fertilization process. We demonstrated nucleic acid presence in prostasomes (both RNA and DNA) and the prostasomal membrane exhibits an unusual composition quantitatively dominated by saturated phospholipids with predominance of sphingomyelin. Prostasome-like microvesicles have been observed in other species including, ram, dog, stallion and boar. Research about the prostasomal microvesicles involves important aspects of the reproduction process and we now highlight the characterization of prostasomes in other mammalian species.
Publications:
Ronquist KG, Carlsson L, Ronquist G, Nilsson S, Larsson A. Prostasome-derived proteins capable of eliciting an immune response in prostate cancer patients. Int J Cancer,2006 119(4):847-53
Ronquist KG, Carlsson L, Ronquist G, Semjonow A, Wülfing C, Larsson A. Serum antibodies against prostasomal clusterin in prostate cancer patients. Scand J Clin Invest, 2008 68(3):219-27
Ronquist KG, Ronquist G, Carlsson L, Larsson A. Human prostasomes contain chromosomal DNA. Prostate, 2009 69(7):737-43
Ronquist KG, Carlsson L, Ronquist G, Larsson A. Proteomic analysis of prostate cancer metastasis-derived prostasomes. Anticancer Res, 2010 30(2):285-90.
Carlsson L, Ronquist KG, Ronquist G, Eliasson R, Egberg N, Larsson A. Association of cystatin C with human prostasomes in seminal plasma. Int J Androl, 2010 33:1-6.
Keywords: Prostasomes, microvesicles, nucleic acid, mammalian species, fertilization.

Roos, Anna; PhD student
Environmental Toxicology, Uppsala University, Uppsala
Principal supervisor: Katrin Lundstedt-Enkel, UU
Keywords: environmental contaminants, health, otters, seals

Rydhmer, Lotta; Agr Dr, Assoc. Professor
Dept. of Animal Breeding and Genetics, SLU, Uppsala
Current research activities:
Animal breeding for sustainable production. Reproduction traits and relations between reproduction and production traits. Piglet production outdoors. Boar taint and behaviour of entire male pigs. Studied traits: puberty in gilts and boars, oestrous symptoms, reproductive disorders, litter size, piglet survival and growth, lactation, sexual, social and maternal behaviour and behaviour related to fear.
Publications:
1. Rydhmer, L. 2000. Genetics of sow reproduction, including puberty, oestrus, pregnancy, farrowing and lactation. Livest. Prod. Sci. 66, 1-12.
2. Rydhmer, L. & Berglund, B. 2006. Selection for reproduction: developments in several species. 8th World Congr. Genet. Appl. Livest. Prod. Belo Horizonte, Brazil. 8 pp. www.wcgalp8.org.br.
3. Imboonta, N, Rydhmer, L & Thumwasorn, S. 2007. Genetic parameters for reproduction and production traits of Landrace sows in Thailand. J. Anim. Sci. vol. 85, 53-59.
4. Rydhmer, L., Lundeheim, N., Canario, L. 2008. Genetic correlations between gestation length, piglet survival and early growth. Livest. Sci. 115, 287-293.
5. Rydhmer, L., Lundström, K. & Andersson, K. 2010. Immunocastration reduces aggressive and sexual behaviour in male pigs. Animal, 4, 965-972.
Keywords: Genetics, piglet survival, maternal behaviour, relations reproduction-production traits.

Sendecka Joanna; MS, PhD student
Dept of Animal Ecology, Evolutionary Biology Centre, Uppsala University, Uppsala
Keywords: Senescence, collared flycatcher, reproductive effort optimization, life-history, allocation of resources.

Sjunnesson, Ylva; DVM, PhD
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Current research activities:
Currently in the scientific field of domestic animal IVF (porcine, bovine and feline). Specific research areas include: impact of stress on porcine oocytes and embryos in an in vivo-in vitro system, confocal laser scanning microscopy studies of oocytes and embryos, impact of various insulin concentrations during maturation of bovine oocytes and the use of single layer sperm centrifugation in porcine IVF. Née Brandt.
Publications:
1. Abraham MC, Gustafsson H, Ruete A, Brandt YC (2012). Breed influences on in vitro
development of abattoir-derived bovine oocytes. Acta Vet Scand. 54:36. [Epub ahead of print]
2. Brandt Y, Einarsson S, Ljung A, Lundeheim N, Rodríguez-Martínez H, Madej A. (2009). Effects of continuous elevated cortisol concentrations during oestrus on concentrations and patterns of progesterone, oestradiol and LH in the sow. Animal Reproduction Science 110, 172–185.
3. Brandt, Y., Lang, A., Madej, A., Rodriguez-Martinez, H., Einarsson, S. (2006). Impact of ACTH administration on the oviductal sperm reservoir in sows: The local endocrine environment and distribution of spermatozoa. Animal Reproduction Science 92, 107–122.
4. Brandt, Y., Lundeheim, N., Madej, A., Rodríguez-Martínez, H., Einarsson, S. (2007). Effects of ACTH injections during estrus on concentrations and patterns of progesterone, estradiol, LH, and inhibin alpha and time of ovulation in the sow. Domestic Animal Endocrinology 32, 122-37.
5. Brandt, Y., Madej, A., Rodríguez-Martínez, H., Einarsson, S. (2007). Effects of exogenous ACTH during oestrus on early embryo development and oviductal transport in the sow. Reproduction in Domestic Animals 42, 118-25.
Keywords: IVF, oocyte, embryo, stress, confocal laser scanning microscopy

Skalkidou, Alkistis;
Dept. of Women’s and Children’s Health, UU, Uppsala.
Current research activities:
My research is aimed at using postpartum depression as a model for atypical depression in women in order to investigate its correlates and risk factors, and especially seasonality trends, association with hormones and genetic polymorphisms. The UPPSAT cohort, assembled in 2006-2007 and consisting of 2.318 women, is being followed and consequences of maternal depression on their children's psycho emotional development will be evaluated. A second cohort is currently being recruited- The BASIC project is an attempt to further extend our knowledge on the pathophysiological processes underlying antenatal depression and postpartum depression (PPD) and also to find predictors of the diseases to improve early recognition. Women are followed by web-based questionnaires (depression rating scales, personality inventory, early life stress, sleep disorders). A randomized sample (n = 250) will be invited to an extensive psychological tests (cognitive tests, attentional bias, prepulse inhibition, blood samples, morning awakening saliva samples) at term pregnancy. Blood and tissue samples will be collected from all women at parturition, and a final assessment of all women will be made six weeks postpartum (similar to the tests at term pregnancy test).
Publications:
1. Postpartum depressive symptoms and the BDNF Val66Met functional polymorphism: effect of season of delivery.
Comasco E, Sylvén SM, Papadopoulos FC, Oreland L, Sundström-Poromaa I, Skalkidou A. Arch Womens Ment Health. 2011 Dec;14(6):453-63. Epub 2011 Oct 14.
2. In vitro fertilization and risk of childhood leukemia in Greece and Sweden.
Petridou ET, Sergentanis TN, Panagopoulou P, Moschovi M, Polychronopoulou S, Baka M, Pourtsidis A, Athanassiadou F, Kalmanti M, Sidi V, Dessypris N, Frangakis C, Matsoukis IL, Stefanadis C, Skalkidou A, Stephansson O, Adami HO, Kieler H.
Pediatr Blood Cancer. 2011 May 25. doi: 10.1002/pbc.23194.
3. Seasonality patterns in postpartum depression.
Sylvén SM, Papadopoulos FC, Olovsson M, Ekselius L, Poromaa IS, Skalkidou A.
Am J Obstet Gynecol. 2011 May;204(5):413.e1-6. Epub 2011 Mar 24.
4. Newborn gender as a predictor of postpartum mood disturbances in a sample of Swedish women. Sylvén SM, Papadopoulos FC, Mpazakidis V, Ekselius L, Sundström-Poromaa I, Skalkidou A.
Arch Womens Ment Health. 2011 Jun;14(3):195-201.
5. Risk of postpartum depression in association with serum leptin and interleukin-6 levels at delivery: a nested case-control study within the UPPSAT cohort.
Skalkidou A, Sylvén SM, Papadopoulos FC, Olovsson M, Larsson A, Sundström-Poromaa I. Psychoneuroendocrinology. 2009 Oct;34(9):1329-37. Epub 2009 May 7.
Keywords: Postpartum depression, leptin, genetic polymorphisms, seasonality, cortisol.

Spörndly-Nees, Ellinor; PhD student
Dept of Anatomy, Physiology and Biochemistry, SLU.
Project title: Analysis of male reproductive tract morphology in reproductive toxicology
Prinicipal supervisor: Lena Holm
Keywords: Male reproduction, reproductive toxicology, endocrine disruptors, testicular histopathology, wild animals.

Stavreus-Evers, Anneli; PhD, Assoc. Prof.
Dept. of Women’s and Children’s Health, Obstetrics & Gynecology, Uppsala University, Uppsala
Current research activities:
My research focus on embryo implantation, endometrial receptivity, embryo development and infertility. I use cell culture models, and bioinformatic tools to study the interaction between the embryo and endometrium. I have compared endometrium from women with unexplained infertility and endometrium from fertile women using array techniques and other biochemical tools. I also study the role of nutrition for embryo development and pregnancy outcome after fertility treatment. Furthermore, prostasomes are studied in relation to embryo implantation and tumor invasion.
Publications:
1. Lusine Aghajanova, Amani Rumman, Signe Altmäe, Kjell Wånggren, Anneli Stavreus-EversDiminished endometrial expression of Ghrelin and Ghrelin Receptor contributes to subfertility in unexplained infertility population Reproductive Sciences 2010 17:823-832.
2. Signe Altmäe. Theodora Kallak, Barbro Fridén, Anneli Stavreus-Evers. Hyaluronan binding protein 2 as a novel target gene in endometrial receptivity Reprod Sci. 2011 18:485-92.
3. S Altmäe, A. Salumets, K. Bjuresten, K. Wånggren, O. Hovatta, A. Stavreus-Evers, Tissue factor and tissue factor pathway inhibitors TFPI-1 and TFPI-2 in human secretory endometrium – link to female infertility Reprod Sci. 2011 18:666-78.
4. Göran K. Ronquist, Anders Larsson, Gunnar Ronquist, Anders Isaksson, Julius Hreinsson, Lena Carlsson, Anneli Stavreus-Evers Prostasomal DNA characterization and transfer into human spermatozoa, Mol Reprod Dev. 2011 78:467-76
5. Altmäe S, Reimand J, Hovatta O, Zhang P, Kere J, Laisk T, Saare M, Peters M, Vilo J, Stavreus-Evers A, Salumets A. Research Resource: Interactome of Human Embryo Implantation: Identification of Gene Expression Pathways, Regulation, and Integrated Regulatory Networks. Mol Endocrinol. 2012 26:203-17.
Keywords: Implantation, Endometrium, Embryo, Prostasomes, Folate

Stigson, Michael; Researcher
Dept. of Pharmaceutical Biosciences, Div. Of Toxicology, Uppsala University, BMC, Uppsala
Keywords:

Strandberg, Erling; AgrDr, Professor
Dept. of Animal Breeding and Genetics, SLU, Uppsala
Keywords: Genetics models, domestic animals.

Ström-Holst, Bodil; DVM, PhD, Dipl ECAR
Dept. of Clinical Sciences, SLU, Uppsala
Current research activites:
Research mainly on canine and feline reproduction and infectious diseases and feline diabetes mellitus. A special interest in canine endocrinology during the oestrous cycle and pregnancy, including diagnostic challenges. An interest also in reproduction of cats, including reproductive performance in breeding cats and diagnostic challenges of the reproductive status of female cats.
Selected publications:
1. Ström Holst B, Frössling J. The Swedish breeding cat: population description, infectious diseases and reproductive performance evaluated by a questionnaire. J Fel Med Surg 2009, 11, 793-802.
2. Ström Holst B, Hagberg M, Lilliehook I, Johannisson A: Expression of four canine leukocyte adhesion factors in fresh and stored whole blood samples evaluated using a no-lyse, no-wash method. Vet Immunol Immunopathol 2011, 139, 271-276.
3. Payan-Carreira R, Pires M, Strom Holst B, Rodriguez-Martinez H: Tumour Necrosis Factor in the Canine Endometrium: An Immunohistochemical Study. Reprod Domest Anim 2011, 46, 410-418.
4. Payan-Carreira R, Santana I, Pires MA, Ström Holst B, Rodriguez-Martinez H. Localization of tumor necrosis factor in the canine testis, epididymis and spermatozoa. Theriogenology 2012, 77, 1540-1548.
5. Ström Holst B, Löfqvist K, Ernholm L, Eld K, Cedersmyg M, Hallgren G. The first case of Brucella canis in Sweden: background, case report and recommendations from a northern European perspective. Acta Vet Scand, 2012, Mar 27; 54:18.
Keywords: canine, feline, endocrinology, pregnancy, infection

Sundberg, Therese; PhD-student
Dept. of Animal Breeding and Genetics, SLU
Keywords: Breeding, fertility, dairy cattle, organic production

Sundström Poromaa, Inger; PhD, Professor
Dept of Women's and Children's Health, Obstetrics and Gynaecology, UU
Current research activities:
The overall aims of my research is to investigate how reproductive hormones influence mood and anxiety in women, how reproductive events affect mood disorders in women, and vice versa, how mood disorders affect reproduction in men and women. My research investigate the interactions between ovarian steroids and mood/anxiety during various aspects of a woman’s fertile life such as young women with adverse mood effects from combined oral contraceptives, pregnant and postpartal women, women with severe premenstrual symptoms, women with postpartum depression, postmenopausal women on estradiol treatment and involuntary childless couples. The study designs span from population-based studies on postpartum depression and its’ genetic component to human experimental studies on anxiety/fear and to neuroimaging studies where functional magnetic resonance imaging is used to evaluate activation of parts of the central nervous system known to be involved in anxiety and/or fear. Furthermore, part of the proposed study is also aiming at elucidating possible harmful effects of progesterone metabolites.
Publications:
1. Wurst FM, Kelso E, Weinmann W, Pragst F, Yegles M, Sundström-Poromaa I. Measurement of Direct Ethanol Metabolites suggests Higher Rate of Alcohol use among Pregnant Women than found with the AUDIT – a Pilot Study in a Population-Based Sample of Swedish Women. Am J Obstet Gynecol, 2008; 198: 407. e1-5.
2. Borgström A, Kask K, Gulinello M, Odlind V, Sundström-Poromaa I. Patients with adverse mood effects from combined oral contraceptives have lower levels of prepulse inhibition than healthy controls. Psychoneuroendocrinology, 2008; 33: 487-96.
3. Kask K, Gulinello M, Bäckström T, Geyer M, Sundström-Poromaa I. Patients with premenstrual dysphoric disorder have increased startle response across both cycle phases and lower levels of prepulse inhibition during the late luteal phase of the menstrual cycle. Neuropsychopharmacology. 2008; 33: 2283-90.
4. Kask K, Bäckström T, Nilsson L-G, Sundström-Poromaa I. Allopregnanolone impairs episodic memory in healthy women. Psychopharmacology (Berl). 2008; 199: 161-8.
5. Volgsten H, Skoog-Svanberg A, Ekselius L, Lundkvist Ö, Sundström-Poromaa I. Prevalence of psychiatric disorders in infertile women and men undergoing in vitro fertilization treatment. Hum Reprod. 2008; 23(9):2056-63.
Keywords: Neurosteroids, CNS, depression, anxiety, fMRI

Svennersten-Sjaunja, Kerstin; PhD, Professor
Dept. of Nutrition and Management, SLU, Kungsängen Research Centre, Uppsala
Current research activities:
The research work is related to milking with the focus on the biology of the dairy cow. It involves both physiological and behavioural responses of the cow during milking as well as udder health. Within our research group we have indicated the importance of the management related to milking, since it influences both the physiology and behaviour of the dairy cow. The effects have rather important consequences for the cow. At present much work is also done in relation to automatic milking systems, where the studies focus on milk quality and uder health. Furthermore the effect of early interaction between the cow and calf is studied with regard to the calf´s behaviour, feed intake and growth and the cow´s milk production and udder health.
We also work with milk production in water buffaloes and with milking and milk quality in developing countries such as Vietnam and Burkina Faso.
Publications:
1. Uvnäs-Moberg, K., Johansson, B., Lupoli, B. and Svennersten-Sjaunja, K. 2001. Oxytocin facilitates behavioural, metabolic and physiological adaptions during lactation. Applied Animal Behaviour Science, 72:225-234.
2. Lupoli, B., Johansson, B., Uvnäs-Moberg, K. and Svennersten-Sjaunja, K. 2001. Effect of suckling on the release of oxytocin, prolactin, cortisol, gastrin, cholecystokinin, somatostatin and insulin in dairy cows and their calves. Journal of Dairy Research, 68:175-187.
3. K. Svennersten-Sjaunja and K. Olsson, Endocrinology of milk production, Domestic Animal Endocrinology, Volume 29, Issue 2, August 2005, 241-258.
4. Thomas CS, Bruckmaier RM, Ostensson K, Svennersten-Sjaunja K. Effect of different milking routines on milking-related release of the hormones oxytocin, prolactin and cortisol, and on milk yield and milking performance in Murrah buffaloes. J Dairy Res. 2005 Feb;72(1):10-8.
5. Wiking L, Nielsen JH, Båvius AK, Edvardsson A, Svennersten-Sjaunja K. Impact of milking frequencies on the level of free fatty acids in milk, fat globule size, and fatty acid composition. J. Dairy Sci. 2006 Mar;89(3):1004-9.
Keywords: Milking technique, lactation physiology, cow-and-calf interaction, udder health.

Svensson, Johan; PhD student
Dept. of Environmental Toxicology, EBC, Uppsala university, Uppsala
Project title: Effects of pharmaceuticals on fish development and reproduction
Principal supervisor: Björn Brunström
Keywords: Fish, endocrine disruption, development, progestins.

Säfholm, Moa; PhD-student
Dept of Environmental Toxicology, EBC, Uppsala University, Uppsala
Project title: Developmental toxicity in amphibians
Principal supervisor: Cecilia Berg
Keywords: Amphibians, endocrine disruption, gonadal differentiation

Söderquist, Lennart; DVM, PhD, Professor, Dipl. ECAR
Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Current research activities:
Further development of AI in small ruminants. Breeding soundness evaluation in young beef bulls. Pheromones for modulating reproduction in cattle. Reproduction in moose.
Publications:
1. Paulenz, H., Söderquist L., T. Ådnoj, A. B. Nordstoga, K. & Andersen Berg, 2005: Effect of vaginal and cervical deposition on the fertility of sheep inseminated with frozen-thawed semen. The Vet rec., 156, 12, 372-375.
2. Persson Y, McGowan M and Söderquist L., 2006: Comparison between the sperm morphology in semen samples obtained from yearling beef bulls by transrectal massage of the ampullae and caudal epididymal dissection. Reprod. Dom. Anim. 41, 233-237.
3. Persson Y, Söderquist L & Ekman S, 2007: Joint disorder; a contributory cause to reproductive failure in beef bulls? Acta Vet Scand. , 49:31
4. Nordstoga AB., Söderquist L., Ådnoy T., Paulenz H. 2010. Fertility Results after Vaginal Deposition of Frozen-Thawed Buck Semen Diluted with Two Different Extenders Using One - or Two-step Procedures. Reproduction in Domestic Animals, 1-5.
5. Nordéus K, Båge R, Gustafsson H, Humblot P, Söderquist L. 2012. The influence of oestrous substances on cyclicity and oestrous behaviour in dairy heifers. Acta Vet Scand. 54:26. doi:10.1186/1751-0147-54-26.
Keywords: Semen, ovine, bovine, artificial insemination, biotechnology.

Tunón, Ann-Marie; DVM, PhD, Lecturer
UDS, Ambulatory Clinic, SLU, Uppsala
Keywords: Gynecology, obstetrics and infections in domestic animals and other species.

Ul Haq, Mazhar; DVM, MSc, Phd student
Dept of Biomedical Sciences and Veterinary Public Health,
Div of Pathology, Pharmacology and Toxicology, SLU.
Project title: The toxicity of the fluorocarboxylic acid Perfluorooctanoic acid (PFOA) in fish.
Principal supervisor: Leif Norrgren
Keywords:

Ullerås, Erik; PhD Assoc professor
Dept of Biomedical Sciences and Veterinary Public Health. Div of Pathology, Pharmacology and Toxicology, SLU, Uppsala
Keywords: Endocrine disruptors, steroidogenesis, developmental toxicity, Zebrafish embryo model.

Wallenbeck, Anna; MSc, PhD
Dept. of Animal Breeding and Genetics, SLU
Funbo-Lövsta, Uppsala, Sweden
Keywords:

Wallgren, Margareta; DVM, PhD, Researcher, Dipl. ECAR
Quality Genetics, Dept. of Clinical Sciences, Division of Reproduction, SLU, Uppsala
Keywords: Andrology, endocrinology and reproductive technology in domestic animals and other species.

Wistedt, Anna; PhD Student
Dept. of Anatomy, Physiology and Biochemistry, SLU, Uppsala
Keywords: Hens, shell formation, Phytoestroens, histochemistry and carbonic anhydrase.

Wånggren, Kjell
Dept of Women's and Children's Health, Obstetrics and Gynaecology, Uppsala University, Uppsala
Keywords:

Yongzhi, Guo; PhD
Div. of Reproduction, Dept. of Clinical Sciences, SLU, Uppsala
Current research activities:
Publications:
Keywords:

Yusnizar, Yulnawati; PhD student
Dept. of Animal Breeding and Genetics, SLU, and Bogor Agricultural University (IPB), Indonesia.
Project title: Spotted buffalo genetic conservation: investigation of coat color variation.
Supervisors: Göran Andersson, Ronny R. Noor, Arief Boediono
Keywords: Coat color gene, epididymal sperm, gametes cryopreservation, artificial insemination, spotted buffalo

Zlabek, Vladimir; PhD
Dept of Food Science, SLU, Uppsala
Current research activities:
Effect of dietary plant oil supplementation on fish physiology. Focus will be on specific steroid hormone levels and detoxification enzyme activity.
Publications:
1. Randak T, Kocour M, Zlabek V, Policar T, Jarkovsky J, 2006: Effect of culture conditions on reproductive traits of brown trout Salmo trutta L. Bulletin Francais De La Peche Et De La Piscicilture (383): 1-11.
2. Randak T, Slavik O, Zlabek V, Kolarova J, Kroupova H, 2006: Juvenile fish - Perspective bioindicators for assesment of the aquatic environment contamination. Toxicology Letters 164: S176-S176 Sp. Iss.
3. Zlabek V, Randak T, Cajka T, Kolarova, J, Svobodova Z, Hajslova J, Jarkovsky J, 2006: Alkylphenols in muscle of fish from rivers in the Czech Republic. Toxicology Letters 164: S177-S177 Sp. Iss.
4. Randak T, Zlabek V, Kolarova J, Svobodova Z, Hajslova J, Siroka Z, Janska M, Pulkrabova J, Cajka T, Jarkovsky J, 2006: Biomarkers detected in Chub (Leuciscus cephalus L.) to evaluate contamination of the Elbe and Vltava rivers, Czech Republic. Bulletin Of Environmental Contamination And Toxicology 76 (2): 233-241.
5. Kolarova J, Svobodova Z, Zlabek V, Randak T, Hajslova J, Suchan P, 2005: Organochlorine and PAHs in brown trout (Salmo trutta fario) population from Ticha Orlice river due to chemical plant with possible effects to vitellogenin expression. Fresenius Environmental Bulletin 14 (12A): 1091-1096.
Keywords: Fish, aquatic pollution, steroid hormones, biomarkers.

Örberg, Jan; PhD, Senior lecturer
Department of Physiology and Developmental Biology, Environmental Toxicology, Uppsala University, Uppsala
Keywords: Endocrinology, nutrition and toxicology in rodents and birds.

Örn, Stefan; PhD
Division of Pathology, Pharmacology and Toxicology, Dept. of Biomedical Sciences and Veterinary Public Health, SLU, Uppsala.
Keywords: Zebrafish, endocrine disruptor, vitellogenin, gonad morphology, sex ratio.

Sidan uppdaterad: 2013-01-01.