The group includes scientists with backgrounds in veterinary medicine, pharmacology, toxicology, biochemistry and bioinformatics. The overall aim is to contribute to sustainable animal welfare and risk assessment of drugs and other xenobiotics. The research objectives are to enhance knowledge on the disposition, effects and mechanisms of action of xenobiotics in different animal species.
Research is performed both on basic mechanism-directed and on applied investigations in cell lines, domestic and laboratory animals. We explore the occurrence and activity of some xenobiotic metabolizing enzymes and transport proteins in the liver and extrahepatic tissues, such as the intestines and the respiratory airways. In vivo studies elucidating the disposition and effects of veterinary drugs are also performed. The research is supported by Foundation for Equine Research (SHF) and by the Swedish Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS).
Education Courses in pharmacology and toxicology are given in the veterinary programme and in master programmes. In addition, degree projects in biology are given.
Collaboration partners are several pre-clinical and clinical research groups at SLU, other Swedish and international universities as well as Swedish Veterinary Institute (SVA). In addition networks are established with authorities including Medical Product Agency (MPA), and branch organisations, such as the Swedish Trotting Association (STC).