CV-sida

Jana M Weiss

Jana Weiss
Environmental and analytical chemist

Presentation

My current research interests are within the field of identification of emerging contaminants using suspect and non-target screening techniques, combining analytical chemistry with toxicological studies in effect-directed analysis, exposure pathways to both the biota and the environment, and environmental ethical questions which we are facing regarding our responsibilities towards future generation and the planet.

Undervisning

I am teaching in courses introducing environmental chemistry on different levels, such as master courses and for a more general public having an interest in the topic. I am supervising PhD students connected to the projects and work for a close collaboration between several Universities.

Forskning

The POPs-group

Professor Karin Wiberg, researcher and leading the POP-group
Associated professor Lutz Ahrens, researcher
Dr Anna-Karin Dahlberg, researcher
Dr Pablo Gago Ferrero, post-doc

Projects

APPLICERA : Applicable site-specific environmental risk assessment of contaminated soils. Cofinanced by FORMAS and the Swedish transport administration (trafikverket) 2015-2017. 

MiSSE : Mixture assessment of Endocrine Disrupting Compounds (EDC) with emphasis on thyroidogenicity – using cats as model for human indoor exposure. Formas 2012-2017.

SUPFES: Substitution in Practice of Prioritized Fluorinated Chemicals to Eliminate Diffuse Sources

Bakgrund

I finished my Ph.D. in environmental chemistry at MMK in Stockholm 2006, mainly focusing on analysis of organic environmental pollutants in a variety of matrices, e.g. blood, milk, food. My thesis was entitled "Human exposure to persistent organic pollutants: Illustrated by four case studies in Europe". Between 2007 and 2009 I had a first post doc position at the Institute for Environmental Studies (IVM) in Amsterdam. The work performed there was implementing the Effect-Directed Analysis (EDA) approach which combines fractionation techniques and bioassays to guide the identification of key toxicants. Much focus was set toward chemical identification strategies of unknown chemicals of concern. I also broadened my experience into toxicology and to use in vitro assays. In 2009 I worked for the Joint Research Centre (JRC) in Ispra, Italy for 2.5 years, at the Institute for Environmental and Sustainability (IES). There I gained insight and experience how to work for the European Commission and was involved in a project supporting the Stockholm Convention to facilitate the Global Monitoring of priority pollutants.  In October 2011 I went back to IVM as senior researcher where I was involved in national and international projects, e.g. PERFOOD (http://www.perfood.eu/), PHARMAS (http://www.pharmas-eu.org/) and SUPFES (http://www.supfes.eu/).

Since 1 April 2016 I have a 60% position at IVM-SLU where I am involved in the coordination of the project APPLICERA, focusing on identification of key-soil quality indexes and soil functions for an improved contaminated soil remediation strategy. 

I have also 40% position at the Department for Environmental Science and Analytical Chemistry (ACES) at Stockholm University, where I co-cordinate the FORMAS supported project MiSSE (Mixture Assessment of EDCs), as well as teach at the Introduction course for Environmental Chemistry (IEC).

Handledning

PhD students (ongoing)

  • Ike van der Veen, IVM, Amsterdam, The Netherlands
  • Kumelachew Mulu Loha, IVM, Amsterdam, The Netherlands
  • Cornelius Rimayi, Wits University, Johannesburg, South Africa
  • Martin Brits, NMISA, Pretoria, South Africa
  • Johannes Pohl, SLU, Uppsala, Sweden (Lic.)

Publikationer i urval

  1. Brits, M., de Vos, J., Weiss, J.M., Rohwer, E.R, and de Boer, J. 2016. Critical review of the analysis of brominated flame retardants and their environmental levels in Africa. Accepted for publication in Chemosphere
  2. Weiss, J.M., Lignell, S., Darnerud, P.O., Kotova, N. Human biomonitoring as a tool toward safe foods – approach at the National Food Agency in Sweden. 2016. European Journal of Nutrition & Food Safety. 6(3);132-147
  3. Rimayi, C.C., Chimuka, L., Odusanya, D., de Boer, J. and Weiss, J.M. 2016. Distribution of 2,3,7,8-substituted polychlorinated dibenzo-p-dioxin and polychlorinated dibenzofurans in the Jukskei and Klip/Vaal catchment areas in South Africa. Chemosphere. 145:314-321
  4. Zhang, J., Kamstra, J., Ghorbanzadeh, M., Weiss, J.M., Hamers, T., Andersson, P. 2015. An in silico approach to identify potential disruptors of the thyroid hormone system among currently known dust contaminants and their metabolites. Environmental Science and Technology. 49:10099-10107
  5. Van der Veen, I., Weiss, J.M., Hanning, A-C., de Boer, J., Leonards, P.E.G. 2015. Development and validation of a method for the quantification of extractable perfluoroalkyl acids (PFAAs) and perfluorooctane sulfonamide (FOSA) in textiles. Talanta. 147:8-15
  6. Weiss, J., De Boer, J., Berger, U., Muir, D., Ruan, T., Torre, A., Smedes, F., Vrana, B., Clavien, F., Fiedler, H. 2015. PFAS analysis in water for the Global Monitoring Plan of the Stockholm Convention – Set-up and guidelines for monitoring. UNEP Chemicals branch, Geneva. http://www.unep.org/chemicalsandwaste/Portals/9/POPs/PFAS/Guide%20PFAS%20water_UNEP%202015.pdf
  7. Weiss, J.M., Andersson, P.L., Zhang, J., Simon, E., Leonards, P.E.G., Hamers, T., Lamoree, M. 2015. Tracing thyroid hormone disrupting compounds: database compilation and structure activity evaluation for an effect-directed analysis of sediment. Analytical and Bioanalytical Chemistry. 407:5625-5634
  8. Schmitt, C., Lamoree, M.H., Leonards, P.E.G., Weiss J.M. and de Deckere E. 2013. In vivo effect confirmation of anti-androgenic compounds in sediment contact tests with Potamopyrgus antipodarum. Journal of Environmental Science and Health A. 48:475-480
  9. Weiss, J.M., van der Veen, I., van Leeuwen, S.P.J., Cofino, W., Crum, S., de Boer, J. 2013. Perfluoroalkyl substances in environmental and food samples - analytical improvements shown over four interlaboratory studies. Trends in Analytical Chemistry 43:204-216
  10. Weiss, J., Mueller, A., Vives, I., Mariani, G. and Umlauf, G. 2013. Spatial gradients of OCPs in European butter- intergrating environmental and exposure information. Environmental Science and Pollution Research International 20(5):2948-2962
  11. Montano, M., Weiss, J., Hoffman, L., Gutleb, A.C., Murk, A.J. 2013. Metabolic activation of nonpolar sediment extracts results in enhanced thyroid hormone disrupting potency. Environmental Science & Technology 47:8878-8886
  12. Meijer, L., Martijn, A., Melessen, J., Brouwer, A., Weiss, J., Jong, F.H. de & Sauer, P.J. 2012. Influence of prenatal organohalogen levels on infant male sexual development: sex hormone levels, testes volume and penile length. Human Reproduction 27(3):867-872
  13. Umbuzeiro, G., Machala, M., Weiss, J. 2011. Diagnostic tools for effect-directed analysis of mutagens, AhR agonists, and endocrine disruptors. Book chapter in “Effect-directed analysis of complex environmental contamination”. Editor W. Brack. Handbook of Environmental Chemistry 15:69-82
  14. Weiss, J.M., Simon, Eszter., Stroomberg, G., de Boer, R., de Boer, J., Van der Linden, S., Leonards, P.E.G., Lamoree, M.H. 2011. Identification strategy for unknown pollutants using high-resolution mass spectrometry: Androgen-disrupting compounds identified through effect-directed analysis. Analytical and Bioanalytical Chemistry 400:3141-3149
  15. Lübcke-von Varel, U., Machala, M., Ciganek, M., Neca, J., Pencikova, K., Vykopalova, L., Vondracek, J., Löffler, I., Streck, G., Reifferscheid, G., Flückiger-Isler, S., Weiss, J.M., Lamoree, M., Brack, W. 2011. Polar compounds dominate in vitro effects of sediment extracts. Environmental Science & Technology 45:2384-2390
  16. Simon, E., Leonards, P.E.G., Balaam, J., Roberts, P., Weiss, J.M., Cenijn, P., Hamers, T., Lamoree, M., de Boer, J. 2010. Testing endocrine disruption in biota samples: a method to remove interfering lipids and natural hormones. Environmental Science & Technology 44:8322-8329
  17. Weiss, J.M., Hamers, T., Thomas, K.V., Van der Linden, S., Leonards, P.E.G. Lamoree, M.H. 2009. Masking effect of anti-androgens on androgenic activity in European river sediment unveiled by effect-directed analysis. Analytical and Bioanalytical Chemistry 394:1385-1397
  18. Weiss, J.M., Andersson, P.L., Lamoree, M.H., Leonards, P.E.G., van Leeuwen, S.P.J., Hamers, T. 2009. Competitive binding of perfluorinated compounds to the thyroid hormone transport protein transthyretin. Toxicological Sciences 109(2):206-216
  19. Meijer, L, Weiss, J, Van Velzen, M, Brouwer, A, Bergman, Å, Sauer, P. 2008. Serum concentrations of neutral and phenolic organohalogens in pregnant women and some of their infants in The Netherlands. Environmental Science & Technology 42:3428-33
  20. Weiss, J., Wallin, E., Axmon, A., Jönsson, B.A.G., Åkesson, H., Athanassiadis, I., Janak, K., Hagmar, L., Bergman, Å. 2006. Hydroxy-PCBs, PBDEs, and HBCDDs in serum from an elderly population of swedish fishermen’s wives and associations with bone density. Environmental Science & Technology 40:6282-6289
  21. Weiss, J., Päpke, O., Bergman, Å. 2005. A worldwide survey of polychlorinated dibenzo-p-dioxins, dibenzofurans, and related contaminants in butter. Ambio 34 (8):589-597
  22. Weiss J., Päpke O., Bignert A., Jensen S., Greyerz E., Agostoni C., Besana R., Riva E., Giovannini M., Zetterström R. 2003. Concentrations of dioxins and other organochlorines (PCBs, DDTs, HCHs) in human milk from Seveso, Milan and a Lombardian rural area in Italy: a study performed 25 years after the heavy dioxin exposure in Seveso. Acta Paediatrica 92:467-472.

Kontaktinformation
Forskare vid Institutionen för vatten och miljö; Sektionen för organisk miljökemi och ekotoxikologi
Telefon: 018-673026, 0725524387
Postadress:
Institutionen för vatten och miljö, Box 7050, 750 07 UPPSALA
Besöksadress: Lennart Hjelms väg 9, Uppsala