During my study at Uppsala university, it is fascinated to get into deep knowledge of different diseases and their molecular mechanisms. As a fresh student after finishing my master programme in Biotechnology, I aimed to join scientific world. With close touch with many scientists, I realize that it needs great ambition, endurable effort and sophistic technique to achieve my goal, I think I am ready for the great challenges.
biomedical basic course
Mainly, i am interested in different enzymes involving the synthesizing pathway of dTTP and their correlation to diseases. Right now, we are focusing on dTMP kinase and Thyimdine kinase 1/2.
In my routine work, I actively perform experimental research by applying different molecular
methods, such as western blot, RT-qPCR, ELISA, immunohistochemistry, molecular cloning, and bioinformatics. Protein, DNA and RNA preparations are frequently carried out in my research. I have very good experiences on different cell cultures and also I have used bacteria as a model for studying diseases.
I have finished my Master programme in Biotechnology at
Uppsala University (UU) 2015 autumn
I worked as a project student at Immunology group of
Department of Medical Biochemistry and Microbiology (IMBIM) at UU since January, 2016 to 2018 august. I have studied allergic diseases and how different factors affect mast cells´ homeostasis and function.Signalling pathway of MAP kinases is one of important projects I have carried out. In order to address our scientific questions, we are using mainly murine mast cells derived from bone marrow stem cells (BMMC) as a model, sometimes also human lung cells and skin biopsies from patients and mice.
Publikationer i urval
Acidic pH is essential for maintaining mast cell secretory granule homeostasis Cell Death & Disease volume 8, page e2785 (2017) doi:10.1038/cddis.2017.206
Copper Regulates Maturation and Expression of an MITF:Tryptase Axis in Mast Cells
J Immunol December 15, 2017, 199 (12) 4132-4141; DOI: https://doi.org/10.4049/jimmunol.1700786
Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules
Front. Immunol., 19 July 2018 | https://doi.org/10.3389/fimmu.2018.01670