OXC-101 treatment in pet dogs with lymphoma or haemangiosarcomaIngress

Last changed: 22 November 2024
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An initial pilot clinical study in dogs with a diagnosis of lymphoma or splenic haemangiosarcoma after splenectomy

Background

As there is no medical treatment registered in the EU for these two indications, dogs with lymphoma or HSA are treated with so-called off-label protocols based on human-registered chemotherapy. All of these have clear side effects. We are striving to find better treatment options for dogs. At the same time, dogs with spontaneous tumours are similar to the human counterpart in many aspects. Therefore, the findings of this study may be valuable for humans with Non Hodgkin's lymphoma (NHL) and/or angiosarcoma which are currently very difficult to treat.

Project overview

An initial pilot clinical study in dogs with a diagnosis of lymphoma or splenic haemangiosarcoma following splenectomy.

Aim with the project

The aim is to see if the given dose of OXC-101 is safe in dogs with lymphoma and/or splenic haemangiosarcoma post operatively. In addition, measurements of signs of efficacy will be collected. Overall, the aim is to find a treatment that improves animal welfare in these tumour conditions, which cause severe suffering and short survival in companion dogs if left untreated.

Facts:

The project is funded by FORMAS and is expected to run between 2023-2025.


Contact

Henrik Rönnberg, professor
Faculty of Veterinary Medicine and Animal Science, SLU
henrik.ronnberg@slu.se, +46(0)18-67 13 63