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KE0073

Biochemistry, continuation

Lectures, teaching sessions, computer practicals, seminars and exercises are used in the course. Some activities are conducted in small groups, while others are not.


Roll call and course introduction, seminars, computer practicals, and group exercises are compulsory components.


Written and oral presentations are carried out through presenting results from computer practicals , seminars and group exercises. The course consists of both biochemical theory and of solving biochemical problem.


The following items are treated in lectures, teaching sessions, seminars and laboratory sessions:



  • technologies for purification, analysis and structural studies of proteins



  • gene technology, bioinformatics, "omics" (genomics, transcriptomics, proteomics, metabolomics), recombinant gene expression



  • enzymes: catalytic mechanisms, regulation of activity, allostery, efficiency, specificity, enzyme-assays



  • carbohydrate metabolism: the pentose phosphate pathway, gluconeogenesis, the glycogen, reciprocal regulation



  • metabolism of fats, lipids, amino acids, proteins, nucleotides, nitrogen metabolism



  • integration of metabolism: nutritional intake, homeostasis, hormonal control, body weight, BMI, overweight, training, starvation, alcohol




-membrane channels, pumps, signal transduction, sensory systems, receptors


Course evaluation

The course evaluation is now closed

KE0073-30062 - Course evaluation report

Once the evaluation is closed, the course coordinator and student representative have 1 month to draft their comments. The comments will be published in the evaluation report.

Additional course evaluations for KE0073

Academic year 2023/2024

Biochemistry, continuation (KE0073-30299)

2024-02-15 - 2024-03-19

Academic year 2021/2022

Biochemistry, continuation (KE0073-30177)

2022-02-18 - 2022-03-23

Syllabus and other information

Grading criteria

After completion of the course students should be able to:

  1. Examine and explain the relationships between structure of a macromolecule, especially of a protein, its biochemical activity and its functional role in a particular biochemical pathway.
  2. Examine and explain the role of a particular biochemical pathway in normal development and disease, at the cellular and organismal levels.
  3. Discuss basic metabolism and integrate major metabolic processes into health and disease states.

Learning goal

Grading criteria

3 (G)

4 (VG)

5 (MVG)

1

Describe how protein activity can be regulated by altering its structure.

Describe and illustrate how protein activity and the whole biochemical pathway can be regulated by altering protein structure.

Correlate protein structure, protein activity and biochemical pathway in the context of normal development and disease, at the cellular and organismal levels.

2

Describe the role of basic biochemical pathways in normal development and disease.

Connect cellular and organismal roles of biochemical pathways in the context of normal development and disease.

3

Describe major metabolic processes and how they are regulated.

Compare major metabolic processes in health versusdisease.

Reflect on health and disease states from metabolome viewpoint.

NB! All compulsory parts of the course should be fulfilled for all grades; i.e. participation in all computer practicals, group exercises, invited seminars and student seminar presentations.

Litterature list

1) Biochemistry
**Link: **

https://www.macmillanlearning.com/ed/uk/product/Biochemistry--9th-edition/p/1319114652


**Authors:** J.M. Berg, J.L. Tymoczko, G.J. Gatto, Jr., L. Stryer 
**ISBN: **978-1-319-11467-1 
**Comments:** Chapter references are given to the 9th edition. Previous editions (8th and 7th) should also work.

Course facts

The course is offered as an independent course: Yes The course is offered as a programme course: Food Science (BSc) Tuition fee: Tuition fee only for non-EU/EEA/Switzerland citizens: 19030 SEK Cycle: Bachelor’s level (G1F)
Subject: Chemistry Biology Chemistry
Course code: KE0073 Application code: SLU-30062 Location: Uppsala Distance course: No Language: Swedish Responsible department: Department of Molecular Sciences Pace: 100%