Cryptosporidium infection dynamics in cattle

Cryptosporidium spp are intracellular parasites in different species, including humans and cattle. C. parvum is considered one of the most common causes of calf diarrhoea and is also a clinically important pathogen in humans. It was recently shown that what has been known as C. parvum in cattle are indeed three different, species; C. parvum, C. bovis and C. ryanae. The overall purpose of the proposed PhD project is to increase the knowledge base of bovine Cryptosporidium infection dynamics. We will investigate how the species distribution pattern varies within a herd and how pathogenic C. bovis is for neonatal calves. We will also clarify which C. parvum subtypes that are present in Swedish cattle herds. The project will yield information regarding the significance of Cryptosporidium infection in cattle herds and their effect on calf health. The information will be used to design tangible advice to farmers on how they can prevent, rather than have to treat, diarrheal disease in the calves and diminish spread of parasites in the herd. This will improve the calf health and also be favorable for the farmers’ economy. A better understanding of the zoonotic potential of our C. parvum infected calves will show if there is a need for improved biosecurity measures for farmers and veterinarians.

Financier: FORMAS
Co-applicant: Ulf Emanuelson Charlotte Silverlås, SLU och SVA Karin Troell, SVA
Collaborator: SVA