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Kursplan

PFS0171 Linear Model, Breeding value, Genomic Selection and Norm of Reaction, 4,0 Hp

Ämnen

Biologi

Utbildningens nivå

Forskarnivå

Språk

Engelska

Förkunskapskrav

Basic training in statistics, computing and genetics or equivalent with a master degree in plant biology.

Mål

The purpose of this course is to familiarise participants with basic and advanced linear models and the latest analytical approaches for quantitative traits. Lectures will give insight into how similarity among relatives can be used to derive quantitative genetics parameters and the estimation and prediction of these parameters including breeding values can be done using mixed linear models. Using modern genomics, how genomic selection can be used to increase selection efficiency. Using both linear and non-linear models, how the norm of the reaction of population and genotypes can be estimated. This will give students a solid foundation in future breeding program design and using genomics and norm of reaction in advanced breeding program for climate adaptation. It covers from basic linear to mixed linear model and their application to breeding value prediction, G by E interaction, genomic selection and modelling of norm of reaction. The basic use of software R and ASReml will be covered and applied to practicals and exercises

Innehåll

Introduction of R

Linear mixed models

Resemblance Among Relatives

Genetic (genotypic) values (Concept and estimation)

Individual tree model

Spatial model and breeding value prediction

Exploratory Marker Data Analysis

Genomic selection

Genotype x Environmental Interactions

Norm of reaction

Ytterligare information

Lectures and demonstration 56 (7 days)

Examination and course evaluation 10 h

Self studies 40 h

Totally 106 h

Ansvarig institution/motsvarande

Institutionen för skoglig genetik och växtfysiologi