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Bengt Guss

Bengt Guss

Selected publications


1.         Löfdahl, S., Guss, B., Uhlén, M., Philipson, L. and Lindberg, M. (1983) Gene for staphylococcal protein A. Proc. Natl. Acad. Sci. USA . 80: 697-701.

2.         Guss, B., Uhlén, M., Nilsson, B., Lindberg, M., Sjöquist, J. and Sjödahl, J. (1984) Region X, the cell wall attachment part of staphylococcal protein A. Eur. J. Biochem. 138: 413-420.

3.         Uhlén, M., Guss, B., Nilsson, B., Gatenbeck, S., Philipson, L. and Lindberg, M. (1984) Complete sequence of the staphylococcal gene encoding protein A, a gene evolved through multiple duplications. J. Biol. Chem. 259: 1695-1702.

4.         Uhlén, M., Guss, B., Nilsson,B., Götz, F. and Lindberg, M. (1984) Expression of the gene encoding protein A in Staphylococcus aureus and coagulase-negative staphylococci. J. Bacteriol. 159: 713-719.

5.         Guss, B., Leander, K., Hellman, U., Uhlén, M., Sjöquist, J. and Lindberg, M. (1985) Analysis of protein A encoded by a mutated gene of Staphylococcus aureus Cowan I. Eur. J. Biochem. 153: 579-585.

6.         Guss, B., Eliasson, M., Olsson, A., Uhlén, M., Frej, A.-K., Jörnvall, H., Flock, J.-I. and Lindberg, M. (1986) Structure of the IgG-binding regions of streptococcal protein G. EMBO J. 5: 1567-1575.

7.         Olsson, A., Eliasson, M., Guss, B., Nilsson, B., Hellman, U., Lindberg, M. and Uhlén, M. (1987) Structure and evolution of the repetitive gene encoding streptococcal protein G. Eur. J. Biochem. 168: 319-324.

8.         Uhlén, M., Nilsson, B., Guss, B., Lindberg, M., Gatenbeck, S. and Philipson, L. (1983) Gene fusion vectors based on the gene coding for staphylococcal protein A. Gene 23: 369-378.

9.         Fahnestock, S. R., Saunders, C. W., Guyer, M. S., Löfdahl, S., Guss, B., Uhlén, M.and Lindberg, M. (1986) Expression of the staphylococcal protein A gene in Bacillus subtilis by integration of the intact gene into the B. subtilis chromosome. J. Bacteriol. 165: 787-795.

10.       Flock, J.-I., Fröman, G., Jönsson,K., Guss, B., Signäs, C., Nilsson, B., Raucci, G., Höök, M., Wadstöm, T. and Lindberg, M. (1987) Cloning and expression of the gene for a fibronectin-binding protein from Staphylococcus aureus. EMBO J. 6: 2351-2357.

11.       Eliasson, M., Olsson, A., Palmcrantz, E., Wiberg, K., Inganäs, M., Guss, B., Lindberg, M. and Uhlén, M. (1988) Chimeric IgG-binding receptors engineered from staphylococcal protein A and streptococcal protein G. J. Biol. Chem. 263: 4323- 4327.

12.       Patti, J. M., Jonsson, H., Guss, B., Switalski, L.M., Wiberg, K., Lindberg, M. and Höök, M. (1992) Molecular characterization and expression of a gene encoding a Staphylococcus aureus collagen adhesin. J. Biol. Chem. 267: 4766-4772.

13.       Lindgren, P.-E., McGavin, M. J., Signäs, C., Guss, B., Gurusiddappa, S., Höök, M. and Lindberg, M. (1993) Two different genes coding for fibronectin-binding proteins from Streptococcus dysgalactiae: The complete nucleotide sequence and characterization of the binding domains . Eur. J. Biochem. 214: 819-827.

14.       Mattsson, J. G., Guss, B. and Johansson, K.-E (1994) The phylogeny of Mycoplasma bovis as determined by sequence analysis of the 16S rRNA gene. FEMS Microbiol. Lett. 115: 325-328.

15.       Jonsson, H., Frykberg, L., Rantamäki, L. and Guss, B. (1994) MAG, a plasma protein receptor from Streptococcus dysgalactiae. GENE, 143: 85-89.

16.       Jonsson, H., Burtsoff-Asp, C. and Guss, B. (1995) Streptococcal protein MAG- a protein with broad albumin binding specificity. Biochim Biophys Acta 1249: 65-71.

17.       Jonsson, H., Lindmark, H. and Guss, B. (1995)  A protein G related cell surface protein in Streptococcus zooepidemicus. Infect Immun 63: 2968-2975.

18.       Lindmark, H. Jacobsson, K., Frykberg, L. and Guss, B. (1996) Fibronectin-binding protein of Streptococcus equi subspecies zooepidemicus. Infect Immun 64: 3993-3999.

19.       Jacobsson, K., Jonsson, H., Lindmark, H., Guss, B., Lindberg, M. and Frykberg. L. (1997) Shot-gun phage display mapping of two streptococcal cell-surface proteins. Microbiol Res.152: 1-8.

20.       Nilsson, M., Frykberg, L., Flock, J.-I., Pei, L., Lindberg, M. and Guss, B. (1998) A fibrinogen-binding protein of Staphylococcus epidermidis. Infect Immun 66: 2666-2673.

21.       Lindmark, H., Jonsson, P., Olsson-Engvall, E. and Guss, B. (1999) Pulsed-field gel electrophoresis and distribution of the genes zag and fnz in isolates of Streptococcus equi. Res Vet Sci. 66: 93-99.

22.       Pei, L., Palma, M., Nilsson, M., Guss, B. and Flock, J-I. (1999) Functional studies of a fibrinogen binding protein from Staphylococcus epidermidis. Infect. Immun. 67: 4525-4530.

23.       Lindmark, H. and Guss, B. (1999) SFS, a novel fibronectin-binding protein from Streptococcus equi, inhibits the binding between fibronectin and collagen. Infect. Immun. 67: 2383-2388.

24.       Tung, H.-S., Guss, B., Hellman, U., Persson, L., Rubin, K. and Rydén, C. (2000) A bone sialoprotein-binding protein from Staphylococcus aureus: a member of the staphylococcal Sdr-family. Biochem. J. 345: 611-619.

25.       Vasi, J., Frykberg, L., Carlsson, E.L. Lindberg, M. and Guss, B. (2000) M-like proteins of Streptococcus dysgalactiae. Infect Immun. 68: 294-302.

26.       Vasi, J., Lindberg, M. and Guss, B. (2000) A novel IS-like element frequently inserted in a putative virulence regulator in bovine mastitis isolates of Streptococcus dysgalactiae. Plasmid. 44: 220-230.

27.       Lindmark, H., Nilsson, M. and Guss, B. (2001) Comparison of the fibronectin-binding protein FNE from Streptococcus equi subspecies equi with FNZ from S. equi subspecies zooepidemicus reveals a major and conserved difference. Infect Immun. 69: 3159-3163.

28.       Lannergård, J., Frykberg, L. and Guss, B. (2003) CNE, a collagen-binding protein of Streptococcus equi. FEMS Microbiol Lett. 222: 69-74.

29.       Nilsson, M., Bjerketorp, J., Wiebensjö, A., Ljungh, Å., Frykberg, L. and Guss, B. (2004) A von Willebrand factor-binding protein from Staphylococcus lugdunensis. FEMS Microbiol Lett. 234: 155-161.

30.       Flock, M., Jacobsson, K., Frykberg, L., Hirst, T.R., Franklin, A., Guss, B., Flock, J.-I. (2004) Recombinant Streptococcus equi proteins protect mice in challenge experiments and induce immune response in horses. Infect Immun. 72: 3228-3236.

31.       Nilsson, M., Bjerketorp, J., Guss, B. and Frykberg, L.(2004) A fibrinogen-binding protein of Staphylococcus lugdunensis. FEMS Microbiol Lett. 241: 87-93.

32.       Karlström, Å., Jacobsson, K., Flock, M., Flock, J.-I. and Guss, B. (2004) Identification of a novel collagen-like protein, SclC, in Streptococcus equi using signal sequence phage display. Vet Microbiol. 104: 179-188.

33.       Lannergård, J., Flock, M., Johansson, S., Flock, J.-I. and Guss, B. (2005) Studies of fibronectin-binding proteins of Streptococcus equi. Infect Immun. 73: 7243-7251.

34.       Lidén, Å., Karlström, Å., Lannergård, J., Kalamajski, S., Guss, B., Rubin, K. and Rydén C. (2006) A fibronectin-binding protein from Streptococcus equi binds collagen and modulates cell-mediated collagen gel contraction. Biochem Biophys Res Commun. 340: 604-610.

35.       Karlström, Å., Jacobsson, K. and Guss, B. (2006) SclC is a member of a novel family of collagen-like proteins in Streptococcus equi subspecies equi that are recognised by antibodies against SclC. Vet Microbiol. 114: 72-81.

36.       Flock, M., Karlström, Å., Lannergård, J., Guss, B. and Flock, J.-I. (2006) Protective effect of vaccination with recombinant proteins from Streptococcus equi subspecies equi in a strangles model in the mouse. Vaccine. 24: 4144-4151.

37.       Lannergård, J. and Guss, B. (2006) IdeE, an IgG-endopeptidase of Streptococcus equi ssp. equi. FEMS Microbiol Lett. 262: 230-235.

38.       Waller, A., Flock, M., Smith, K., Robinson, C., Mitchell, Z., Karlström, Å., Lannergård, J., Bergman, R., Guss, B. and Flock, J.-I. (2007) Vaccination of horses against strangles using recombinant antigens from Streptococcus equi. Vaccine. 25: 3629-3635.

39.       Lidén Å, van Wieringen, T., Lannergård, J., Kassner, A., Heinegård, D., Reed, R.K., Guss, B. and Rubin, K. (2008) A secreted collagen- and fibronectin-binding streptococcal protein modulates cell-mediated collagen gel contraction and interstitial fluid pressure. J Biol Chem. 283: 1234-1242.

40.       Hulting, G., Flock, M., Frykberg, L., Lannergård, J., Flock, J.-I. and Guss, B. (2009) Two novel IgG endopeptidases of Streptococcus equi. FEMS Microbiol Lett. 298: 44-50.

41.       Guss, B., Flock, M., Frykberg, L., Waller, A.S., Robinson, C., Smith, K.C. and Flock, J.-I. (2009) Getting to grips with strangles: an effective multi-component recombinant vaccine for the protection of horses from Streptococcus equi infection. PLoS Pathog. 2009 Sep;5(9):e1000584. Epub 2009 Sep 18. PubMed PMID: 19763180.

42.       Rönnberg, E., Guss, B. and Pejler, G. (2010) Infection of mast cells with live streptococci causes a toll-like receptor 2- and cell-cell contact-dependent cytokine and chemokine response. Infect Immun. 78: 854-864.

 43.      Rosengren, Å., Fabricius, A., Guss, B., Sylvén, S. and Lindqvist, R. (2010) Occurrence of foodborne pathogens and characterization of Staphylococcus aureus in cheese produced on farm-dairies. Int J Food Microbiol. 144:263-269.

44.       van Wieringen, T., Kalamajski, S., Lidén, A., Bihan, D., Guss, B., Heinegård, D., Farndale R.W. and Rubin, K. (2010) The streptococcal collagen-binding protein CNE specifically interferes with αVβ3-mediated cellular interactions with triple helical collagen. J Biol Chem. 285:35803-35813.

45.       Rosander, A., Guss, B. and Pringle, M. (2011) An IgG-binding protein A homolog in Staphylococcus hyicus. Vet Microbiol. 149:273-276.

46.       Rosander, A., Guss, B., Frykberg, L., Björkman, C., Näslund, K. and Pringle, M. (2011) Identification of immunogenic proteins in Treponema phagedenis-like strain V1 from digital dermatitis lesions by phage display. Vet Microbiol. 153:315-322

47.       Flock, M., Frykberg, L., Sköld, M., Guss, B. and Flock, J.-I. (2012) Antiphagocytic function of an IgG glycosyl hydrolase from Streptococcus equi subsp. equi and its use as a vaccine component. Infect Immun. 80:2914-2919.

48.       García-Faroldi, G., Rönnberg, E., Orro, A., Calounova, G., Guss, B., Lundequist, A. and Pejler, G. (2013) ADAMTS: novel proteases expressed by activated mast cells. Biol Chem. 394:291-305.

49.       Rönnberg, E., Calounova, G., Guss, B., Lundequist, A. and Pejler, G. (2013) Granzyme D is a novel murine mast cell protease that is highly induced by multiple pathways of mast cell activation. Infect Immun. 81:2085-2094.

50.       Rönnberg, E., Johnzon, C.F., Calounova, G., Faroldi, G.G., Grujic, M., Hartmann, K., Roers, A., Guss, B., Lundequist, A. and Pejler, G. (2014) Mast cells are activated by Staphylococcus aureus in vitro but do not influence the outcome of intraperitoneal Staphylococcus aureus infection in vivo. Immunology. 143:155-63. doi: 10.1111/imm.12297

51.       Reyhani, V., Seddigh, P., Guss, B., Gustafsson, R., Rask, L. and Rubin, K. (2014) Fibrin binds to collagen and provides a bridge for αVβ3 integrin-dependent contraction of collagen gels. Biochem J. 462:113-23. doi: 10.1042/BJ20140201

52.       Johnzon, C.F., Rönnberg, E., Guss, B.and Pejler, G. (2016) Live Staphylococcus aureus Induces Expression and Release of Vascular Endothelial Growth Factor in Terminally Differentiated Mouse Mast Cells. Front Immunol. 7:247. doi: 10.3389/fimmu.2016.00247.

53.       Johnzon, C.F., Artursson, K., Söderlund, R., Guss, B., Rönnberg, E. and Pejler, G. (2016) Mastitis Pathogens with High Virulence in a Mouse Model Produce a Distinct Cytokine Profile In Vivo. Front Immunol. 7:368.

54.       Bjerketorp, J., Levenfors, J.J., Sahlberg, C., Nord, C.L., Andersson, P.F., Guss, B., Öberg B. and Broberg, A. (2017) Antibacterial 3,6-Disubstituted 4-Hydroxy-5,6-dihydro-2H-pyran-2-ones from Serratia plymuthica MF371-2. J Nat Prod. 80:2997-3002. doi: 10.1021/acs.jnatprod.7b00565.

55.       Robinson, C., Frykberg, L., Flock, M., Guss, B., Waller, A.S. and Flock, J.-I. (2018) Strangvac: A recombinant fusion protein vaccine that protects against strangles, caused by Streptococcus equi. Vaccine. 36:1484-1490. doi: 10.1016/j.vaccine.2018.01.030.

56.       Lidén, Å., Karlsen, T.V., Guss, B., Reed, R.K. and Rubin, K. (2018) Integrin αV β3 can substitute for collagen-binding β1 -integrins in vivo to maintain a homeostatic interstitial fluid pressure. Exp Physiol. 2018 May 1;103(5):629-634. doi: 10.1113/EP086902.




Professor emeritus at the Department of Biomedical Science and Veterinary Public Health; Division of Bacteriology and Food Safety
Postal address:
BVF, Bakteriologi och livsmedelssäkerhet, Box 7036
Visiting address: Ulls väg 26, Uppsala