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Mikael Brandström Durling

Mikael Brandström Durling
The main focus of my research is within the area of genome evolution.

Presentation

Current high throughput sequencing methods combined with the small genome sizes of fungi provides a sweet spot where the complete genomes of large numbers of individuals and related species can be compared in order to address questions of how and why the DNA sequences change over time. I am currently using species from the Heterobasidion species complex as model organisms for this work.

SCATA - Analysis framework for the analysis of sequenced tagged amplicons, typically derived from high throughput sequencing of microbial communities.

Selected publications

Publications in Peer Reviewed Journals

Wallander, H., Johansson, U., Sterkenburg, E., Brandström Durling, M., & Lindahl, B. D. (2010). Production of ectomycorrhizal mycelium peaks during canopy closure in Norway spruce forests. The New phytologist, 187(4), 1124-34. doi: 10.1111/j.1469-8137.2010.03324.x.

Lira, J., Linderholm, A., Olaria, C., Brandström Durling, M., Gilbert, M. T., Ellegren, H., et al. (2010). Ancient DNA reveals traces of Iberian Neolithic and Bronze Age lineages in modern Iberian horses. Molecular ecology, 19(1), 64-78. doi: 10.1111/j.1365-294X.2009.04430.x.

Malmström, H., Gilbert, M. T., Thomas, M. G., Brandström, M., Storå, J., Molnar, P., et al. (2009). Ancient DNA reveals lack of continuity between neolithic hunter-gatherers and contemporary Scandinavians. Current biology : CB, 19(20), 1758-62. doi: 10.1016/j.cub.2009.09.017.

Brandström, M., & Ellegren, H. (2008). Genome-wide analysis of microsatellite polymorphism in chicken circumventing the ascertainment bias. Genome research, 18(6), 881-7. doi: 10.1101/gr.075242.107.

Brandström, M., Bagshaw, A. T., Gemmell, N. J., & Ellegren, H. (2008). The relationship between microsatellite polymorphism and recombination hot spots in the human genome. Molecular biology and evolution, 25(12), 2579-87. doi: 10.1093/molbev/msn201.

Axelsson, E., Hultin-Rosenberg, L., Brandström, M., Zwahlén, M., Clayton, D. F., Ellegren, H., et al. (2008). Natural selection in avian protein-coding genes expressed in brain. Molecular ecology, 17(12), 3008-17. doi: 10.1111/j.1365-294X.2008.03795.x.

Väli, U., Brandström, M., Johansson, M., & Ellegren, H. (2008). Insertion-deletion polymorphisms (indels) as genetic markers in natural populations. BMC genetics, 9(1), 8. doi: 10.1186/1471-2156-9-8.

Brandström, M., & Ellegren, H. (2007). The genomic landscape of short insertion and deletion polymorphisms in the chicken (Gallus gallus) Genome: a high frequency of deletions in tandem duplicates. Genetics, 176(3), 1691-701. doi: 10.1534/genetics.107.070805.

Valdiosera, C. E., García, N., Anderung, C., Dalén, L., Crégut-Bonnoure, E., Kahlke, R., et al. (2007). Staying out in the cold: glacial refugia and mitochondrial DNA phylogeography in ancient European brown bears. Molecular ecology, 16(24), 5140-8. doi: 10.1111/j.1365-294X.2007.03590.x.

Backström, N., Brandström, M., Gustafsson, L., Qvarnström, A., Cheng, H., Ellegren, H., et al. (2006). Genetic mapping in a natural population of collared flycatchers (Ficedula albicollis): conserved synteny but gene order rearrangements on the avian Z chromosome. Genetics, 174(1), 377-86. doi: 10.1534/genetics.106.058917.

Berlin, S., Brandström, M., Backström, N., Axelsson, E., Smith, N. G., Ellegren, H., et al. (2006). Substitution rate heterogeneity and the male mutation bias. Journal of molecular evolution, 62(2), 226-33. Springer New York. doi: 10.1007/s00239-005-0103-6.

Smith, N. G., Brandström, M., & Ellegren, H. (2004). Evidence for turnover of functional noncoding DNA in mammalian genome evolution. Genomics, 84(5), 806-13. doi: 10.1016/j.ygeno.2004.07.012.

International Chicken Genome Sequencing Consortium. (2004). Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature, 432(7018), 695-716. doi: 10.1038/nature03154.

Wong, G. K., Liu, B., Wang, J., Zhang, Y., Yang, X., Zhang, Z., et al. (2004). A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature, 432(7018), 717-22. doi: 10.1038/nature03156.


Contact
Researcher at the Department of Forest Mycology and Plant Pathology; Division of Forest Pathology
Telephone: +4618-671503
Postal address:
Skoglig mykologi och växtpatologi , Box 7026
750 07 UPPSALA
Visiting address: Almas Allé 5, Uppsala
Page editor: cajsa.lithell@slu.se