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Parisa Norouzitallab

Research

Epigenetics is the study of reversible changes in gene function that occur without modifications in the DNA sequence. The epigenetic variations that are environmentally determined, contribute to inter-individual variation in gene expression and thus to variation in development of phenotypes in an individual or even throughout the entire population. These epigenetic modifications can in some cases be inherited by subsequent generations, even when the initial external stimuli is no longer present in the environment of these organisms. My research interests are focused on 1) probing the epigenetic mechanisms behind development of phenotypes that can be inherited to subsequent generation/s with a focus on innate immunity and trained immunity in crustaceans, 2) development of epigenetic markers for evaluating the efficiency of an individual product or feed in terms of immune stimulation.

 

 

Cooperation

Ghent University

Background

Fisheries, Fish & Shellfish  health management, Epigenetics, Trained immunity 

Supervision

M. Sc thesis   completed 12, Post‐doctoral fellows and visiting research associates:  completed 2

 

PhD undergoing 1:

Mrs. Suvra Roy (India; 2016-present). Promoter of the thesis provisionally entitled “Probing the immunological and molecular mechanisms of transgenerational immune priming in crustaceans, using gnotobiotic brine shrimp A. franciscana as model organism”. Ghent University, Belgium. 

Selected publications

1. Norouzitallab, P., Baruah, K., Vanrompay, D., Bossier, P.  (2018). Teaching Shrimps Self-Defense to Fight Infections. Trends in Biotechnology. 37: 1: 16 -19. 

2. Norouzitallab, P., Baruah, K., Vanrompay, D., Bossier, P.  (2018). Can epigenetics translate environmental cues into phenotypes? Science of The Total Environment. 647: 1281-1293. IF: 4.9 

3. Martín-Rodríguez, J. A., Álvarez-Méndez, S. J., Overå, C., Baruah, K., Margarida Lourenço. T., Norouzitallab, P., Bossier, P.,  Martín, V. S., Fernández, J. J. (2018). The 9H-Fluoren Vinyl Ether Derivative SAM461 Inhibits Bacterial Luciferase Activity and Protects Artemia franciscana From Luminescent Vibriosis. Frontiers in Cellular and Infection Microbiology. 8: 368. 

4. Baruah, K.,  Norouzitallab, P., Phong HP.,  Smagghe G., Bossier, P. (2017). Enhanced resistance against Vibrio harveyi infection by carvacrol and its association with the induction of heat shock protein 72 in gnotobiotic Artemia franciscana. Cell Stress and Cheperones. 22: 377-387.

5. Norouzitallab, P., Baruah, K., Biswas, P., Vanrompay, D., Bossier, P.  (2016). Probing the phenomenon of trained immunity in invertebrates during a transgenerational study, using brine shrimp Artemia as a model system. Scientific Reports. 15: 6: 21166.

6. Pestana, J., Novais, S., Norouzitallab, P., Vandegehuchte, M. B., Bossier. P., De Schamphelaere, K (2016). Non-lethal heat shock increases tolerance to metal exposure in brine shrimp. Environmental Research. 151: 663-670. 

7. Norouzitallab, P., Biswas, P., Baruah, K & Bossier, P. (2015). Multigenerational immune priming in an invertebrate parthenogenetic Artemia to a pathogenic Vibrio campbellii. Fish & Shellfish Immunology. 42: 2: 426 - 429.  

8. Norouzitallab, P., Baruah, K., Muthappa, D. M & Bossier P. (2014). Non-lethal heat shock induces HSP70 and HMGB1 protein production sequentially to protect Artemia franciscana against Vibrio campbellii. Fish & Shellfish Immunology. 42: 2: 395 – 399. 

9. Norouzitallab, P., Baruah, K .,  Vandegehuchte, M.,  Van Stappen, G., Catania, F.,  Vanden Bussch, J., Vanhaecke, L., Sorgeloos, P & Bossier, P. (2014). Environmental heat stress induces epigenetic transgenerational inheritance of robustness in parthenogenetic Artemia model. FASEB journal. 28: 8: 3552-3563.

10.*Baruah, K., *Norouzitallab, P., Linayati, L., Sorgeloos, P & Bossier, P. (2014). Reactive oxygen species generated by a heat shock protein (Hsp) inducing product contributes to Hsp70 production and Hsp70-mediated protective immunity in Artemia franciscana against pathogenic vibrios. Developmental & Comparative Immunology. 46: 2: 470 - 479.

11. *Niu, Y. F. *Norouzitallab, P., Baruah, K., Dong, S. L & Bossier, P. (2014). A plant-based heat shock protein inducing compound modulates host-pathogen interactions between Artemia franciscana and Vibrio campbellii. Aquaculture. 430: 120 – 127.  

Links

https://biblio.ugent.be/person/802000975389

https://www.researchgate.net/profile/Parisa_Norouzitallab

 


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