Stina Ekman
Presentation
Professor emerita, DVM, PhD, diplomate of ECVP
Published articles the last 5 years
- Mäkeläinen S, Ekman S, Hytönen MK, Lohi H, Kyöstilä K, Simon T, Andersson G, Hedhammar Å, Hansson K, Bergström TF. A nonsense mutation in the PRKG2 gene in dalmatian dogs with chondrodysplasia. PLoS One. 2025 Nov 26;20(11):e0322107. doi: 10.1371/journal.pone.0322107. eCollection 2025.PMID: 41296694 §
- Jacobson M, Berglund M, Pettersson M, Sandström M, Matti F, Sjölund M, Backhans A, Ytrehus B, Ekman S. Pathological and bacteriological findings in sows, finisher pigs, and piglets, being culled for lameness. Porcine Health Manag. 2025 Oct 13;11(1):49. doi: 10.1186/s40813-025-00463-4.PMID: 41084038
- Olstad K, Ekman S, Björnsdóttir S, Fjordbakk CT, Hansson K, Sigurdsson SF, Ley CJ. Osteochondrosis in the central and third tarsal bones of young horses. Vet Pathol. 2024 Jan;61(1):74-87. doi: 10.1177/03009858231185108. Epub 2023 Jul 11.PMID: 37431760
- Kendall A, Ekman S, Skiöldebrand E.J. Nerve growth factor receptors in equine synovial membranes vary with osteoarthritic disease severity. Orthop Res. 2023 Feb;41(2):316-324. doi: 10.1002/jor.25382. Epub 2022 May 31.PMID: 35578994
- Löfgren M, Ekman S, Ekholm J, Engström M, Fjordbakk CT, Svala E, Holm Forsström K, Lindahl A, Skiöldebrand E. Conditioned serum in vitro treatment of chondrocyte pellets and osteoarthritic explants. Equine Vet J. 2023 Mar;55(2):325-335. doi: 10.1111/evj.13582. Epub 2022 Jun 6.PMID: 35514185
- Adepu S, Ekman S, Leth J, Johansson U, Lindahl A, Skiöldebrand E. Biglycan neo-epitope (BGN262), a novel biomarker for screening early changes in equine osteoarthritic subchondral bone. Osteoarthritis Cartilage. 2022 Oct;30(10):1328-1336. doi: 10.1016/j.joca.2022.07.005. Epub 2022 Jul 21.PMID: 35870736
- Torbjörn M, Amela T, Andreas T, Stina E, Cecilia L, Caroline ÖM, Petra HJ, Marianne JW, Patricia H. Guided bone tissue regeneration using a hollow calcium phosphate based implant in a critical size rabbit radius defect. Biomed Mater. 2021 Mar 3;16(3). doi: 10.1088/1748-605X/abde6f.PMID: 33477115
- Hedenqvist P, Trbakovic A, Mellgren T, Öhman-Mägi C, Hammarström Johansson P, Manell E, Ekman S, Ley C, Jensen-Waern M, Thor A. The effect of housing environment on bone healing in a critical radius defect in New Zealand White rabbits. PLoS One. 2020 May 21;15(5):e0233530. doi: 10.1371/journal.pone.0233530. eCollection 2020.PMID: 32437406
Research
The aim of the research
To find, create and use biomarkers for inflammatory, anabolic, catabolic, and painful processes in connection with OA and OC, in order to detect the tissue changes early and hence be able to prevent development of chronic irreversible damage to the joints. The studies aim to delineate the early development with progression towards chronic tissue destruction, in order to understand the pathogenesis. This knowledge is crucial when trying to prevent chronic damage in OA and OC joints.
On-going research projects
Identification of unique protein fragments found in inflamed articular cartilage in vitro. In addition, evaluate if these molecules are present in serum and synovial fluids from animals with early subclinical joint lesions of OA and OC diseases. The aim of the research is to design a biomarker panel for clinical use, detecting early reversible joint lesions. The research is also translational aiming to detect early joint lesions in man. The project is a collaboration between SLU (Professor Eva Skiöldebrand) and Sahlgrenska Akademin, Gothenburg (Professor Anders Lindahl).