Joakim Bjerketorp
Presentation
Since 2021, I have been a researcher at the Department of Animal Biosciences, SLU, in a university-industry collaboration funded by Intervacc AB (https://intervacc.se/en/research/). My main focus is on developing recombinant vaccines for key bacterial diseases in horses (Streptococcus equi; Streptococcus zooepidemicus), pigs (Streptococcus suis), and cattle (Staphylococcus aureus) and on accompanying serological tests (ELISA) that can differentiate between infected and vaccinated animals (DIVA). Earlier research on novel antibiotics, antimicrobial discovery and nucleoside analogue repurposing continues as a minor part.
Research
Current projects:
Development of recombinant vaccines against Streptococcus suis in pigs and Staphylococcus aureus in cattle (Intervacc funding).
Streptococcus equi and strangles in horses – further investigation of Strangvac and development of upgraded diagnostics (Intervacc funding).
Development of an improved and objective diagnostic tool for digital dermatitis in cattle. (Seydlitz MP Companies Foundation 2023-2025; Project leader Anna Rosander, SLU).
Research projects
- Sow vaccination with a novel recombinant protein vaccine protects piglets against Streptococcus suis infection
- Improved and objective diagnostic tool for digital dermatitis in cattle and footrot/contagious ovine digital dermatitis in sheep
Former research
Selected former project:
The SLU–Ultupharma (https://www.ultupharma.se/) project “New antibiotics from nature”, with the aim set on developing methods to discover new antibiotics effective against pathogenic bacteria resistant to current clinical treatments. It spanned traditional microbiological culturing, innovative techniques for cultivating previously uncultivable microorganisms, exploring methods to stimulate microbes to produce a wider range of bioactive compounds, screening, isolating and characterizing novel putative antibiotics against relevant resistant bacteria (Biobo/Ultupharma 2015-2019; Project leader Anders Broberg, SLU).
Publications
2025 Neutralisation of the Immunoglobulin-Cleaving Activity of Streptococcus equi Subspecies equi IdeE by Blood Sera from Ponies Vaccinated with a Multicomponent Protein Vaccine
2025 Sow vaccination with a novel recombinant protein vaccine protects piglets against Streptococcus suis infection Research article (Peer reviewed)
2025 Repurposing zidovudine and 5-fluoro-2′-deoxyuridine as antibiotic drugs made possible by synergy with both trimethoprim and the mitochondrial toxicity-reducing agent uridine Research article (Peer reviewed)
2024 Digital dermatitis in Swedish dairy herds assessed by ELISA targeting Treponema phagedenis in bulk tank milk Research article (Peer reviewed)
2022 Tetramic acid based alkaloids from Aspergillus amoenus Roberg strain UP197-antibiotic properties and new pyranterreones Research article (Peer reviewed)
2021 In-peptide amino acid racemization via inter-residue oxazoline intermediates during acidic hydrolysis Research article (Peer reviewed)
2021 Selective Isolation of Multidrug-Resistant Pedobacter spp., Producers of Novel Antibacterial Peptides Research article (Peer reviewed)
2020 Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria Research article (Peer reviewed)
2020 Isolation of antibiotic-resistant bacteria in biogas digestate and their susceptibility to antibiotics Research article (Peer reviewed)
2020 Antibacterial pyrrolidinyl and piperidinyl substituted 2,4-diacetylphloroglucinols from Pseudomonas protegens UP46 Research article (Peer reviewed)
Antibacterial Isoquinoline Alkaloids from the Fungus Penicillium Spathulatum Em19
2019 Antibacterial Isoquinoline Alkaloids from the Fungus Penicillium Spathulatum Em19 Research article (Peer reviewed)
2018 Formulation and stabilization of an Arthrobacter strain with good storage stability and 4-chlorophenol-degradation activity for bioremediation Research article (Peer reviewed)
2017 Antibacterial 3,6-Disubstituted 4-Hydroxy-5,6-dihydro-2H-pyran-2-ones from Serratia plymuthica MF371-2 Research article (Peer reviewed)
Labradorins with antibacterial activity produced by Pseudomonas sp.
2017 Labradorins with antibacterial activity produced by Pseudomonas sp. Research article (Peer reviewed)
2013 Effects of di- and polysaccharide formulations and storage conditions on survival of freeze-dried Sphingobium sp. Research article (Peer reviewed)
Soft inertial microfluidics for high throughput separation of bacteria from human blood cells
2009 Soft inertial microfluidics for high throughput separation of bacteria from human blood cells Research article (Peer reviewed)
Rapid lab-on-a-chip profiling of human gut bacteria
2008 Rapid lab-on-a-chip profiling of human gut bacteria Research article (Peer reviewed)
Advances in preservation methods: keeping biosensor microorganisms alive and active
2006 Advances in preservation methods: keeping biosensor microorganisms alive and active Review article (Peer reviewed)
A von Willebrand factor-binding protein from Staphylococcus lugdunensis.
2004 A von Willebrand factor-binding protein from Staphylococcus lugdunensis. Research article (Peer reviewed)
The von Willebrand factor-binding protein (vWbp) of Staphylococcus aureus is a coagulase
2004 The von Willebrand factor-binding protein (vWbp) of Staphylococcus aureus is a coagulase Research article (Peer reviewed)
Sorting a Staphylococcus aureus phage display library against ex vivo biomaterial
2004 Sorting a Staphylococcus aureus phage display library against ex vivo biomaterial. Research article (Peer reviewed)
A fibrinogen-binding protein of Staphylococcus lugdunensis
2004 A fibrinogen-binding protein of Staphylococcus lugdunensis Research article (Peer reviewed)
Shotgun Phage Display - Selection for Bacterial Receptins or other Exported Proteins.
2003 Shotgun Phage Display - Selection for Bacterial Receptins or other Exported Proteins. Research article (Peer reviewed)
Phage display as a novel screening method to identify extracellular proteins.
2002 Phage display as a novel screening method to identify extracellular proteins. Research article (Peer reviewed)
A novel von Willebrand factor binding protein expressed by Staphylococcus aureus
2002 A novel von Willebrand factor binding protein expressed by Staphylococcus aureus Research article (Peer reviewed)
Novel adhesive proteins of pathogenic Staphylococci and their interaction with host proteins
2004 Novel adhesive proteins of pathogenic Staphylococci and their interaction with host proteins Doctoral thesis