Peter Bozhkov
Presentation
We are interested in the mechanisms and functions of catabolic processes during plant development, aging and stress response at the molecular, cellular and organismal levels. We are studying autophagy, proteolysis, biomolecular condensates, and chloroplast calcium-mediated signaling.
Research
Ten selected publications
Zou Y, Sabljić I, Horbach N, Dauphinee AN, Åsman A, Sancho Temino L, Minina EA, Drag M, Stael S, Poreba M, Ståhlberg J, Bozhkov PV. Thermoprotection by a cell membrane-localized metacaspase in a green alga. Plant Cell. 2024 Feb 26;36(3):665-687. doi: 10.1093/plcell/koad289.
Solis-Miranda J, Chodasiewicz M, Skirycz A, Fernie AR, Moschou PN, Bozhkov PV, Gutierrez-Beltran E. Stress-related biomolecular condensates in plants. Plant Cell. 2023 Sep 1;35(9):3187-3204. doi: 10.1093/plcell/koad127.
Gutierrez-Beltran E, Elander PH, Dalman K, Dayhoff GW 2nd, Moschou PN, Uversky VN, Crespo JL, Bozhkov PV. Tudor staphylococcal nuclease is a docking platform for stress granule components and is essential for SnRK1 activation in Arabidopsis. EMBO J. 2021 Sep 1;40(17):e105043. doi: 10.15252/embj.2020105043.
Minina EA, Dauphinee AN, Ballhaus F, Gogvadze V, Smertenko AP, Bozhkov PV. Apoptosis is not conserved in plants as revealed by critical examination of a model for plant apoptosis-like cell death. BMC Biol. 2021 May 12;19(1):100. doi: 10.1186/s12915-021-01018-z.
Minina EA, Staal J, Alvarez VE, Berges JA, Berman-Frank I, Beyaert R, Bidle KD, Bornancin F, Casanova M, Cazzulo JJ, Choi CJ, Coll NS, Dixit VM, Dolinar M, Fasel N, Funk C, Gallois P, Gevaert K, Gutierrez-Beltran E, Hailfinger S, Klemenčič M, Koonin EV, Krappmann D, Linusson A, Machado MFM, Madeo F, Megeney LA, Moschou PN, Mottram JC, Nyström T, Osiewacz HD, Overall CM, Pandey KC, Ruland J, Salvesen GS, Shi Y, Smertenko A, Stael S, Ståhlberg J, Suárez MF, Thome M, Tuominen H, Van Breusegem F, van der Hoorn RAL, Vardi A, Zhivotovsky B, Lam E, Bozhkov PV. Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases. Mol Cell. 2020 Mar 5;77(5):927-929. doi: 10.1016/j.molcel.2019.12.020.
Gutierrez-Beltran E, Moschou PN, Smertenko AP, Bozhkov PV. Tudor staphylococcal nuclease links formation of stress granules and processing bodies with mRNA catabolism in Arabidopsis. Plant Cell. 2015 Mar;27(3):926-43. doi: 10.1105/tpc.114.134494.
Minina EA, Filonova LH, Fukada K, Savenkov EI, Gogvadze V, Clapham D, Sanchez-Vera V, Suarez MF, Zhivotovsky B, Daniel G, Smertenko A, Bozhkov PV. Autophagy and metacaspase determine the mode of cell death in plants. J Cell Biol. 2013 Dec 23;203(6):917-27. doi: 10.1083/jcb.201307082.
van Doorn WG, Beers EP, Dangl JL, Franklin-Tong VE, Gallois P, Hara-Nishimura I, Jones AM, Kawai-Yamada M, Lam E, Mundy J, Mur LA, Petersen M, Smertenko A, Taliansky M, Van Breusegem F, Wolpert T, Woltering E, Zhivotovsky B, Bozhkov PV. Morphological classification of plant cell deaths. Cell Death Differ. 2011 Aug;18(8):1241-6. doi: 10.1038/cdd.2011.36.
Sundström JF, Vaculova A, Smertenko AP, Savenkov EI, Golovko A, Minina E, Tiwari BS, Rodriguez-Nieto S, Zamyatnin AA Jr, Välineva T, Saarikettu J, Frilander MJ, Suarez MF, Zavialov A, Ståhl U, Hussey PJ, Silvennoinen O, Sundberg E, Zhivotovsky B, Bozhkov PV. Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome. Nat Cell Biol. 2009 Nov;11(11):1347-54. doi: 10.1038/ncb1979.
Bozhkov PV, Filonova LH, Suarez MF. Programmed cell death in plant embryogenesis. Curr Top Dev Biol. 2005;67:135-79. doi: 10.1016/S0070-2153(05)67004-4.