Perfluorooctane sulfonate (PFOS) exposure of bovine oocytes affects early embryonic development at human-relevant levels in an in vitro model
This study demonstrates, for the first time, consequences of Perfluorooctane sulfonate (PFOS) exposure during oocyte maturation for early embryonic development. The article stands out for its thorough characterisation of functional, morphological and molecular effects of PFOS in an innovative and human-relevant bovine in vitro model. The findings are relevant for human reproductive health and are the product of a collaboration between SLU and UU, thus lying at the core of CRU’s scope.
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Hallberg, I., Persson, S., Olovsson, M., Sirard, M. A., Damdimopoulou, P., Rüegg, J., & Sjunnesson, Y. C. B. (2021). Perfluorooctane sulfonate (PFOS) exposure of bovine oocytes affects early embryonic development at human-relevant levels in an in vitro model. Toxicology, 464, 153028.