2023

Date: 2023-12-14

A CRU webinar with PhD student Pongpreecha Malaluang, Department of Clinical Sciences, SLU.

Anna is a veterinarian and defended her PhD thesis September 29 at SLU, Department of Animal Nutrition and Management.

• Date: 2023-12-13

• Date: 2023-12-07

Full title:Unveiling Developmental Neurotoxicity – Bridging Gaps from Epidemiology to Molecular Pathways

A CRU webinar with Andrea Cediel Ulloa, Ph.D. student, Uppsala University, Department of Organismal Biology.

Pongpreecha Malaluang will present his work “Antimicrobial resistance of the microbiota in the reproductive tract of horses in conjunction with assisted reproduction”. Pongpreecha Malaluang is a veterinarian with his degree from Khon Kaen University, Thailand, and he began his PhD studies at SLU in 2019.

• Date:2023-11-01

CRU supported symposium, satellite to Uppsala Health Summit 2023: Chemical Pollution and One Health: How do we move from reactivity to proactivity?

Uppsala Health Summit (UHS) 2023 (24–25 Oct.) is dedicated to one of the most pressing issues with regards to human and planetary health: chemical pollution. Under the title “Chemical Pollution and One Health: From reactivity to proactivity” scientists, policy-makers, and regulators and other key stakeholder will gather to discuss the critical next steps and how to speed up efforts.

After the UHS 2023, on 26 October, the Satellite Symposium on Chemical Pollution and One Health will take place, with some of the key invited speakers at the UHS. The symposium aims at further discuss the topic and the identified next steps at the summit.

The symposium is free of charge and open to all interested scientists from the natural/life sciences and social sciences, as well as other stakeholders. It is organized by Uppsala University, the Swedish University of Agricultural Sciences, the Centre for Reproductive Biology in Uppsala (CRU), and CLL. It is taking place at the Evolutionary Biology Center, Uppsala University.

Greetings from the organizing committee,

Ida Hallberg, SLU
Mikael Karlsson, UU
Joëlle Rüegg, UU
Diana Lupu, UU

Preliminary schedule

9.00-12.15 Presentations of invited speakers

• Juliette Legler, Prof. of Toxicology, Utrecht University
• Leonardo Trasande, Prof. of Pediatrics, New York University
• Tom Zoeller, Emeritus Prof. of Biology, University of Massachusetts, Amherst
• Josep Jimenez-Chillaron, Senior researcher, University of Barcelona
• Åke Bergman, Senior Prof. of Environmental Chemistry, Örebro University
• Shirlee Tan, Senior toxicologist for the Seattle and King County Public Health Department
• Mikael Karlsson, Assoc. Prof. of Environmental Sciences, Uppsala University
• Baskut Tuncak, Director of the Massachusetts Toxics Use Reduction Institute (TBC)

12.15-13.15 Lunch (at own expenses)

13.15-15.15 Roundtable discussions: How do we move from reactivity to proactivity?

• Group discussions on both toxicological/chemical and legal/policy aspects

15.30-16.30 Discussion in plenum and Conclusion

Full title: CRU Webinar: Antimicrobial resistance of the microbiota in the reproductive tract of horses in conjunction with assisted reproduction

A CRU webinar with PhD student Pongpreecha Malaluang, Department of Clinical Sciences, SLU.

Pongpreecha Malaluang will present his work “Antimicrobial resistance of the microbiota in the reproductive tract of horses in conjunction with assisted reproduction”. Pongpreecha Malaluang is a veterinarian with his degree from Khon Kaen University, Thailand, and he began his PhD studies at SLU in 2019.

• Date: 2023-10-25 

The seminar is arranged by the Department of Animal Nutrition and Management, SLU, and the Centre for Reproductive Biology in Uppsala, CRU.

• Contact person is Renée Båge.
• Date: 2023-09-28

• Date: 2023-09-14–15

• Date: 2023-08-21 

The networking meeting was Monday morning 21/8 at Evolutionary Biology Center (EBC), Uppsala University and included interesting talks by the invited key note speaker Michael Skinner and early career CRU members as well as networking opportunities during the poster exhibition and lunch at Hassan’s restaurant EBC.

• Date: 2023-08-21 

Report

The meeting took place at EBC in the Zootis hall on 21st of August 2023. It started with a key note presentation given by Professor Michael Skinner from Center for Reproductive Biology, School of Biological Sciences Washington State University, Pullman WA. The subject of the talk was how environmental factors, by impacting an individual, can alter the health of future generations via epigenetic mechanisms. In the coffee break, there was a poster session. 
Five of the ten posters were presented by PhD students, participating in a competition. The judges of the competition, professors Joëlle Rüegg (UU) and Göran Andersson (SLU), interviewed the contestants carefully. After the break, the first-authors of the two best peer-reviewed papers during 2021-2022, were awarded: Ida Hallberg and Emmanouil Tsakoumis. This was followed by presentations of the winning papers and five 6-min talks by PhD students. 

The networking meeting was concluded with lunch at Hassan’s restaurant at EBC where the judges of the poster competition awarded the winner, Andrea Cediel Ulloa. 

The scientific committee met after the lunch.

Program

09.00-10.00 Welcome and key note presentation: Michael K. Skinner “Environmental Impacts on Epigenetic Transgenerational Inheritance: Generational Toxicology and Reproductive Disease Etiology”

10.00-10.30 Fika + Poster exhibition: Presenters stay near their posters (10 posters)

10.45-12.00 Awarding of winners for best CRU peer-reviewed articles 2021-2022 and oral presentations

• Ida Hallberg SLU (Best article at SLU) “Perfluorooctane sulfonate (PFOS) exposure of bovine oocytes affects early embryonic development”
• Violeta de Anca Prado UU “Genetic and germ line methylomic dynamics following a multigenerational exposure related to metabolic diseases” 
• Josef Dahlberg SLU “Mammary gland disease in dairy cows” 
• Andrea Cediel-Ulloa UU “Development of an in vitro method for the assessment of endocrine disruption-induced developmental neurotoxicity” 
• Emmanouil Tsakoumis UU (Best article at UU) “Impaired leptin signaling results in subfertility in female zebrafish”
• Hedvig Stenberg SLU “A high-throughput sequencing study on Swedish boar semen–the microbiome” Nadja Visser UU “Effect of phthalates on endometrial cells”

12.00-13.30 Networking lunch in Hassan’s VIP room (continued poster exhibition) and awarding of poster presentation winner

13.30-15.00 CRU VK meeting (only the scientific committee)

• Date: 2023-06-15

Full title: CRU symposium: Bovine Reproduction in the 20s: Towards sustainable livestock production

• Date: 2023-06-15 

Topics and speakers

• Contribution of sire fertility status to the establishment of pregnancy in cattle. Sean Fair, University of Limerick. 
• Cytomics in fertility prediction. Marc Yeste, University of GIrona
• Cryopreservation of bovine oocytes and embryos: cellular and molecular changes. Teresa Mogas, University of Barcelona.
• Implementation of some natural bioactive molecules with strong antibacterial activity in the treatment of bacterial mastitis in cows - theoretical and practical considerations. Dusan Misic, University of Wroclav.

• Date 2023-06-12–16
• 1.5 ECTS.

The subjects covered were reproductive endocrinology in various species, both sexes, different developmental stages, and gestation. Comparative aspects of reproductive endocrinology in humans and animals were an important part of the course.

Read more at the website of Uppsala University.

Full title: The effect of drugs and other chemicals on embryonic cardiac function in a rat model.

A CRU Webinar with invited speaker Assoc Prof Helen Ritchie.

Assoc Prof Helen Ritchie is an academic at The University of Sydney, Australia, where she teaches anatomy. Her research is in the field of Teratology where she uses in vitro and in vivo methods to explore the role of hypoxia as a cause of adverse developmental outcomes.

Webinar summary: Slowing embryonic heart rate has been associated with embryonic death and malformations. We use two methods to identify potential cardiotoxic agents (i) whole rat embryo culture and (ii) high speed ultrasonography of pregnant rats. In this webinar, I introduce these methods and show some of our results.

• Date: 2023-05-10 

Full title: Station med mikroskop, förevisning av hundspermier och grisoocyter i samband med kosläpp på SLUs försöksgård Lövsta.

• Date: 2022-05-06

A CRU seminar with invited speaker Prof Sezgin Gunes.

Prof Sezgin Gunes is an academic at Ondokuz Mayis University, Turkiye, where she teaches medical biology and genetics. Her research interests are genetic and epigenetic mechanisms underlying common human diseases, especially male infertility and urological malignancies.

Seminar summary: Toxic exposures have various effects, including intrauterine growth retardation, developmental disruption, congenital defects, miscarriages, fetal death, and infertility. This seminar will introduce the mechanisms of teratogenesis and how toxic agents cause developmental disruption in mammals and humans. Risk assessment principles and practices associated with health risks will be discussed.

• Date: 2023-04-27

• Date: 2023-04-25

Full title: Identification of bull semen microbiota and possible alternatives for antibiotics in semen extender.

• Speaker: Aleksandar Cojkic, PhD student at the Department of Clinical Sciences, SLU.
• Date: 2023-03-22

Full title: Milk pregnancy-associated glycoproteins as indicators of pregnancy maintenance in dairy cattle.

• Speaker: Patricia Ask Gullstrand, PhD student at the Department of Animal Breeding and Genetics, SLU.
• Date: 2023-02-08 

• Speaker: PhD student Hedvig Stenberg at the Department of Biomedical Science and Veterinary Public Health; Virology unit at SLU, Uppsala
• Date: 2023-01-25

• Date: 2023-01-24