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Parisa Norouzitallab

Parisa Norouzitallab

Presentation

Epigenetics is the study of reversible changes in gene expression and function that occur without modifications in the DNA sequence. The epigenetic variations that are environmentally determined contribute to inter-individual variation in gene expression and, thus, to variation in the development of phenotypes in an individual or even throughout the entire population. These epigenetic modifications can, in some cases, be inherited by subsequent generations, even when the initial external stimuli are no longer present in the environment of these organisms. My research interests are focused on 1) probing the epigenetic mechanisms behind the development of phenotypes that can be inherited by subsequent generation/s with a focus on innate immunity and trained immunity in crustaceans, 2) development of epigenetic markers for evaluating the efficiency of an individual product or feed in terms of immune stimulation.

 

Live brine shrimp Nauplii. Photo.

Teaching

  • Course coordinator and leader since 2021: Epigenetics Management of Stress and Disease, Uppsala University (2 credits)
  • Lecturer since 2022: Advanced Animal Nutrition, SLU (MSc level; 15 credits)
  • Lecturer since 2021: Sustainable Aquaculture, SLU (MSc level;15 credits)
  • Lecturer in 2021: Basic Animal Breeding and Genetics, SLU (30 credits)
  • Lecturer since 2021: Aquaculture Genetics, UGent, Belgium (MSc level; 5 credits).

Research

To address my research questions, I have been using Artemia as a model organism. Artemis is a small crustacean with a short generation time. It produces dormant eggs that can be stored for months without losing viability. The property which is unique and is mostly described for plant models. 

Cooperation

Terengganu University, Malaysia

Gorgan University  and Urmia University, Iran

Ghent University, Belgium

Uppsala University, Sweden

Chulalongkorn University, Thailan

Background

  • B.Sc in Natural Resource Engineering - Fisheries Science, Tehran University, Iran (2003 -2007)
  • M.Sc in Aquaculture, Ghent University, Belgium (2008 -2010)
  • Ph.D in Applied Biological Sciences, Ghent University, Belgium (2010 -2015)
  • Postdoc 1. Lab of Immunology and Animals Biotechnology, Ghent University, Belgium (2015 - 2018).
  • Postdoc 2. Lab of Immunology and Animals Biotechnology, Ghent University, Belgium (2018 - present)
  • Postdoc 3. Department of Physiology and Environmental Toxicology, Uppsala University, Sweden (2020 - 2022)
  • Postdoc 4. Aquaculture and Nutraceutical Research Group, Swedish University of Agricultural Sciences, Sweden (2021 - present)
  • Cofounder of Artemia germ-free lab, SLU
  • Co-founder of germ-free rainbow trout larvae lab, SLU

Supervision

(co) supervisor of 14 master's students - Completed

(co) supervisor of 4 PhD students - 1 completed and 3 undergoing

Selected publications

  • Roy, S., Baruah, K., Bossier, P., Vanrompay, D., Norouzitallab, P (2022). Induction of transgenerational innate immune memory against Vibrio infections in a brine shrimp (Artemia franciscana) model. Aquaculture (In press).
  • De Vos, S., Rombauts, S., Coussement, L., Dermauw, W., Vuylsteke, M., Sorgeloos, P., Clegg, J., ambu, Z., Van Nieuwerburgh, F., Norouzitallab, P., Van Leeuwen, T., De Meyer, T., Van Stappen, G., Van de Peer, Y., Bossier, P (2021). The genome of the extremophile Artemia provides insight into strategies to cope with extreme environments. BMC Genomics. 22: 635. 
  • Nursaliza Yaacob*, E., Norouzitallab, P*., De Geest, BG., Bajek, A., Dierckens, K., Bossier, P., Vanrompay, D (2020). Recombinant DnaK Orally Administered Protects Axenic European Sea Bass Against Vibriosis. Frontiers in Immunology. 10:3162. *Shared first authorship.
  • Norouzitallab, P., Baruah, K., Vanrompay, D., Bossier, P. (2019). Can epigenetics translate environmental cues into phenotypes? Science of the Total Environment. 647: 1281-1293.
  • Roy, S., Kumar V., Bossier, P*., Norouzitallab, P*., Vanrompay, D* (2019). Phloroglucinol treatment induces transgenerational epigenetic inherited resistance against Vibrio infections and thermal stress in a brine shrimp (Artemia franciscana) model. Frontiers in Immunology. 10: 2745.
  •  Norouzitallab, P., Baruah, K., Vanrompay, D., Bossier, P. (2019). Teaching Shrimps Self-Defense to Fight Infections. Trends in Biotechnology. 37: 1: 16 -19. IF: 19.536.
  • Norouzitallab, P., Baruah, K., Biswas, P., Vanrompay, D., Bossier, P.  (2016). Probing the phenomenon of trained immunity in invertebrates during a transgenerational study, using brine shrimp Artemia as a model system. Scientific Reports. 15: 6: 21166. IF: 4.9.
  • Norouzitallab, P., Biswas, P., Baruah, K & Bossier, P. (2015). Multigenerational immune priming in an invertebrate parthenogenetic Artemia to a pathogenic Vibrio campbellii. Fish & Shellfish Immunology. 42: 2: 426 - 429.  IF: 4.2.
  • Norouzitallab, P., Baruah, K., Muthappa, D. M & Bossier P. (2014). Non-lethal heat shock induces HSP70 and HMGB1 protein production sequentially to protect Artemia franciscana against Vibrio campbellii. Fish & Shellfish Immunology. 42: 2: 395 – 399.  IF: 4.43.
  • Pestana, J., Novais, S., Norouzitallab, P., Vandegehuchte, M. B., Bossier. P., De Schamphelaere, K (2016). Non-lethal heat shock increases tolerance to metal exposure in brine shrimp. Environmental Research. 151: 663-670.  IF: 6.94.

 


Contact

Postdoctor at the Department of Animal Nutrition and Management; Aquaculture
Postal address:
Box 7024
75007 Uppsala
Visiting address: Ulls väg 26, Uppsala

Publications list: