A brown and white dog. Photo.
Responsible use of sulfonamide antibiotics can reduce the need for more critically important antibiotics, helping to combat antimicrobial resistance. Photo: Carl Ekstrand

How sulfonamide antibiotics affect dogs and cats

Page reviewed:  09/06/2026

There has been concern about side effects from sulfonamide antibiotics used to treat infections in dogs and cats. However, serious adverse reactions are uncommon, according to new research from the Swedish University of Agricultural Sciences (SLU). Some dog breeds are more susceptible than others.

Read the full article in Swedish. 

The English text has been translated using AI.

Link to the scientific publication:

Ekstrand, C., Hedlund, M., Pelander, L. et al. Adverse events of trimetroprim-sulphonamide treatment of cats and dogs: a systematic review. Vet Res Commun 50, 224 (2026). 

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