Translational and comparative medicine

New surgical methods of benefit to both humans and animals
The materials mean that we don't have to harvest donor tissue (in humans, bone tissue is usually taken from the hip bone; in dogs, we usually harvest it from the "upper arm bone" humerus). Instead, those synthetic ceramic materials can be used, man-made bone graft material.

Unlocking precision diagnostics and targeted therapies for osteoarthritis
Our translational research has identified novel OA specific biomarkers that are conserved across species, including humans. We have developed diagnostic assays to analytically validate and quantify these biomarkers in body fluids from both horses and humans.

Win-win for both animal and human patients
Early clinical results are highly encouraging: several dogs have shown measurable tumor regression with minimal to no side effects. This is particularly promising, as there are currently no licensed veterinary treatments specifically for these cancer types, despite their poor prognosis and significant impact on canine welfare.

“Mini-guts” show how parasites infect and how probiotics can help fight them
We’re building “mini-guts” in the lab from horse and dog cells to study how parasites infect and how probiotics can help fight them. The aim is to find sustainable alternatives to drugs, which parasites are rapidly becoming resistant to.

Why do bacterial species sometimes cause harm and sometimes not?
All bodies carry bacteria – some vital, others dangerous. Why does the same species behave differently? Homayoon Davam is investigating this in a project on poultry and E. coli. (in Swedish)