Biochemistry, continuation
The course is aimed at those who wish to learn more about molecular regulation of biological processes during normal development and disease. The lectures are interspersed with practical exercises and brainstorming seminars so that you will have the best possible conditions to grasp biochemical principles through discussing and reflecting on their relevance to everyday life. The previous knowledge in the basics of chemistry is required.
Remarkable precision, perfection and logic of biomolecules and biochemical pathways achieved during evolution underlie all aspects of surrounding life and human activities. Likewise, scientific progress in biochemistry is immense and is a driving force of medicine, biotechnology, agriculture, and food industry among other areas. Irrespective of what path of career you will chose in future, biochemical knowledge will always help and sometimes will be even critically necessary in problem-solving.
Instead of providing you with all-embracing theoretical knowledge of biochemistry, which would take many years of studies, the course shall rather make you interested in the subject
and help navigate you in finding explanations for various biological phenomena. Furthermore, the course will facilitate your better understanding of cell biology, immunology and genetics, i.e. other subjects closely related to biochemistry.
Course evaluation
The course evaluation is now closed
KE0064-30256 - Course evaluation report
Once the evaluation is closed, the course coordinator and student representative have 1 month to draft their comments. The comments will be published in the evaluation report.
Additional course evaluations for KE0064
Academic year 2019/2020
Biochemistry, continuation (KE0064-30056)
2020-02-20 - 2020-03-24
Academic year 2018/2019
Biochemistry, continuation (KE0064-30114)
2019-02-21 - 2019-03-25
Academic year 2017/2018
Biochemistry, continuation (KE0064-30006)
2018-02-12 - 2018-03-25
Academic year 2016/2017
Biochemistry, continuation (KE0064-30002)
2017-02-13 - 2017-03-26
Syllabus and other information
Syllabus
KE0064 Biochemistry, continuation, 7.5 Credits
Biokemi, fortsättningskursSubjects
Chemistry BiologyEducation cycle
Bachelor’s levelModules
Title | Credits | Code |
---|---|---|
Single module | 7.5 | 0201 |
Advanced study in the main field
First cycle, has less than 60 credits in first-cycle course/s as entry requirementsBachelor’s level (G1F)
Grading scale
The grade requirements within the course grading system are set out in specific criteria. These criteria must be available by the course start at the latest.
Language
SwedishPrior knowledge
Knowledge and skills in fundamentals of chemistry corresponding to 15 hpObjectives
The aim of the course is to give advanced knowledge and skills within biochemistry.
On completion of the course, the student should be able to:
account at a general level for different technologies for analysis and structural studies of proteins
describe and illustrate principles of enzyme catalysis, kinetics and regulation
identify structural and functional parts in protein stuctures and relate to the function of the protein (e g catalytic mechanism at enzymes, receptor mechanism)
account at a general level for methods to generate and use biological information (gene technology and bioinformatics)
describe how lipids carbohydrates and proteins are metabolized and synthesised
present and discuss metabolism in connection with overweight nutritional intake, training, starvation, diabetes
relate symptoms on deficit/surplus/genetic defects to metabolic disturbances at a biochemical level
present biochemical problem-solving in the form of seminars
carry out basic biochemical experiments according to instruction, to analyse results obtained and to present these in writing
Content
Lectures, teaching sessions, laboratory sessions, seminars and exercises are used in the course.
Course introduction, laboratory introduction, seminar, certain exercises as well as laboratory sessions and presentations of these are compulsory components.
Written and oral presentations are carried out through presentations of laboratory results and at seminar presentations.
The course consists of both biochemical theory and of biochemical laboratory sessions.
The following items are treated in lectures, teaching sessions, seminars and laboratory sessions:
technologies for purification, analysis and structural studies of proteins
gene technology, bioinformatics, "omics" (genomics, transcriptomics, proteomics, metabolomics), recombinant gene expression
enzymes: catalytic mechanisms, regulation of activity, allosteri, efficiency, specificity, enzyme-assays
-carbohydrate metabolism: the pentose phosphate pathway, gluconeogenesis, the glykogen, reciprocal regulation
metabolism of fats, lipids, amino acids, proteins, nucleotides, nitrogen metabolism
integration of metabolism: nutritional intake, homeostasis, hormonal control, body weight, BMI, overweight, training, starvation, alcohol
-membrane channels, pumps, signal transduction, sensory systems, receptors
Grading form
The grade requirements within the course grading system are set out in specific criteria. These criteria must be available by the course start at the latest.Formats and requirements for examination
Examination formats: Written examination, compulsory presentations of laboratory components and of written assignments, compulsory laboratory components and written assignments.
Passing the course requires:
Approved examination, approved laboratory reports and passed written assignments and approved participation in compulsory activities.
- If a student has failed an examination, the examiner has the right to issue supplementary assignments. This applies if it is possible and there are grounds to do so.
- The examiner can provide an adapted assessment to students entitled to study support for students with disabilities following a decision by the university. Examiners may also issue an adapted examination or provide an alternative way for the students to take the exam.
- If this syllabus is withdrawn, SLU may introduce transitional provisions for examining students admitted based on this syllabus and who have not yet passed the course.
- For the examination of a degree project (independent project), the examiner may also allow the student to add supplemental information after the deadline for submission. Read more in the Education Planning and Administration Handbook.
Other information
The right to participate in teaching and/or supervision only applies for the course instance the student was admitted to and registered on.
If there are special reasons, students are entitled to participate in components with compulsory attendance when the course is given again. Read more in the Education Planning and Administration Handbook.
Additional information
The entry requirements can be achieved e g by having followed the courses in basic chemistry I and II comprising in total 22.5 credits with at least 15 credits passed results.Some learning activities may be conducted in English.
Responsible department
Department of Molecular Sciences
Further information
Grading criteria
After completion of the course students should be able to:
- Examine and explain the relationships between structure of a macromolecule, especially of a protein, its biochemical activity and its functional role in a particular biochemical pathway.
- Examine and explain the role of a particular biochemical pathway in normal development and disease, at the cellular and organismal levels.
- Discuss basic metabolism and integrate major metabolic processes into health and disease states.
Learning goal |
Grading criteria |
||
3 (G) |
4 (VG) |
5 (MVG) |
|
1 |
Describe how protein activity can be regulated by altering its structure. |
Describe and illustrate how protein activity and the whole biochemical pathway can be regulated by altering protein structure. |
Correlate protein structure, protein activity and biochemical pathway in the context of normal development and disease, at the cellular and organismal levels. |
2 |
Describe the role of basic biochemical pathways in normal development and disease. |
Connect cellular and organismal roles of biochemical pathways in the context of normal development and disease. |
|
3 |
Describe major metabolic processes and how they are regulated. |
Compare major metabolic processes in health versusdisease. |
Reflect on health and disease states from metabolome viewpoint. |
NB! All compulsory parts of the course should be fulfilled for all grades; i.e. participation in all computer practicals, group exercises, invited seminars and student seminar presentations.
Litterature list
- Biochemistry Författare: J.M. Berg, J.L. Tymoczko, G.J. Gatto, Jr., L. Stryer ISBN: 978-1-319-11467-1 [Biochemistry] (https://www.macmillanlearning.com/college/us/product/Biochemistry/p/1319114679) Kommentar: Sidhänvisningar ges till senaste upplagan 9th edition. Tidigare upplagor 8th och 7th ed fungerar också.