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Syllabus

PVS0163 Comparative reproductive biotechnologie, 2.0 Credits

Subjects

Biology

Education cycle

Postgraduate level

Grading scale

Prior knowledge

Persons admitted to, or have completed, a postgraduate program in animal science, reproduction, biology, medicine,veterinary medicine, food science, nutrition, or related subjects, or to a specialist training program (e.g. resident) or equivalent within the same subjects. A basic understanding of reproductive biology is needed

Objectives

The aim of the course is to expand the participants’ knowledge and understanding of reproductive biotechnologies in vertebrate animals andhumans. Comparative aspects of reproductive biotechnologies in humans and animals will be covered. Learning outcomes: After completing the course the student shall be able to: 1) Explain how to manipulate basic reproductive endocrinology 2) Describe the different reproductive biotechnologies (e.g.) - Artificial insemination - Embryo production in vitro and in vivo and embryo transfer -Preservation, cryopreservation and vitrification Cloning and gene targeting -Intracytoplasmic sperm injection and other gamete manipulations 3) Explain the principles of cryobiology 4) Discuss potential epigenetic effects of reproductive biotechnologies 5) Discuss species differences and similarities in reproductive biotechnologies 6) Discuss aspects of security and biosecurity in relation to reproductive biotechnologies 7) Discuss aspects of reproductive biotechnologies in relation to the student´s own work 8) Discuss ethical aspects of the use of reproductive biotechnologies

Content

The contents will include the following topics (including comparative aspects): Overview on gamete production and collection, male and female Update on how to prepare females for assisted reproductive technologies (ART) Gamete quality and factors affecting gamete quality Sperm selection methods to improve sperm quality Embryo production in vivo and in vitro Transgenesis, cisgenesis, gene targeting and potential epigenetic effects Reproductive strategies in wild populations and conservation breeding Ethics and animal welfare Pedagogical form: The course will include lectures, group discussions and practical sessions. A preliminary schedule is attached.

Additional information

The course will be given in collaboration with the Centre for Reproductive Biology in Uppsala, the Cell for Life Platform and the Developmental Biology Platform SLU. There will be a pre‐course assignment consisting of reading the scientific articles and preparing an oral presentation for the other students at the start of the course summarizing how reproductive biotechnologies relates to their own project. A written summary of how their own work relates to reproductive biotechnologies must be sent in before the course starts. Target audience: PhD students and residents. Others that are interested are also welcome. Time: One week 2020 (preliminary schedule is attached for timetable) Costs: There is no course fee. The participants will cover their own travel and living costs. Application: Via GS‐VMAS. For further information, contact course organizers: Ylva.Sjunnesson@slu.se (course leader); Jane.Morrell@slu.se; Eva.Axner@slu.se; Stefan.Orn@slu.se; Gunnar.Carlsson@slu.se

Responsible department

Department of Clinical Sciences