Our research is focused on the role of catabolic pathways such as RNA degradation and proteolysis, particularly in relation to cell development and stress responses. We pursue multilevel and multidisciplinary approaches, ranging from the organismal level down to single molecules.
-Role of proteolysis in cell polarity and fate decisions
-Protein and RNA (RNPs) complexes during development
Selected Recent Publications
Moschou PN*, Gutierrez-Beltran E, Bozhkov PV, Smertenko A (2016) Separase Promotes Microtubule Polymerization by Activating CENP-E-Related Kinesin Kin7. Dev. Cell 37(4): 350–61. *Corresponding author (comment in: Link)
Moschou PN*, Savenkov EI, Minina EA, Fukada K, Reza HS, Gutierrez-Beltran E, Sanchez-Vera V, Suarez MF, Hussay PJ, Smertenko AP, Bozhkov PV (2016) EXTRA SPINDLE POLES (Separase) controls anisotropic cell expansion in Norway spruce (Picea abies) embryos independently from its role in anaphase progression. New Phytol. In Press. *Corresponding author
Alvarez JM, Sohlberg J, Engström P, Zhu T, Englund M, Moschou PN, von Arnold S. (2015) The WUSCHEL-RELATED HOMEOBOX 3 gene PaWOX3 regulates lateral organ formation in Norway spruce. New Phytol. 208(4):1078-88.
Gutierrez-Beltran E, Moschou PN*, Smertenko AP, Bozhkov PV. (2015) Tudor staphylococcal nuclease links formation of stress granules and processing bodies with mRNA catabolism in Arabidopsis. Plant Cell 27(3):926-43. *Corresponding author
Zhu T, Moschou PN, Alvarez JM, Sohlberg JJ, von Arnold S. Wuschel-related homeobox 8/9 is important for proper embryo patterning in the gymnosperm Norway spruce. (2014) J. Exp. Bot. 65(22):6543-52.
Moschou PN*, Smertenko AP, Minina EA, Fukada K, Savenkov EI, Robert S, Hussey PJ, Bozhkov PV. (2013) The caspase-related protease separase (extra spindle poles) regulates cell polarity and cytokinesis in Arabidopsis. Plant Cell 25(6):2171-86. *Corresponding author