Jump to main content

The organic chemistry group

We perform research within "Metabolomics" and "Biomolecules structure and interactions". We host the NMR and MS platforms at SLU-Uppsala and are providing expertise to many projects. Our NMR platform is the metabolomics node of the national NMR research infrastructure SwedNMR involving 10 universities and supported by the national research council VR-RFI.

Group members

Head of unit:

Corine Sandström, Professor

Researchers

Tatiana Agback, Researcher

Anders Broberg, Professor (web page)

Jan Eriksson, Senior researcher

Ali Moazzami, Senior researcher

Jolanta Levenfors , Researcher

Anders Sandström, Senior lecturer

Research engineers:

Peter Agback, NMR

Suresh Gohil, Mass spectrometry

Post Docs:

Hanna Eriksson Röhnisch

Tahereh Jafari 

PhD students:

Elin Alexandersson

Yan Xue

Group photo organic chemistry

Alumni

Rolf Andersson

Dr. Christina Nord

Dr. Johnny Östman

Dr. Lena Lundqvist

Dr. Frida Wende

Dr. Gustav Nestor

Dr. Eric Morssing Vilen

Dr. Pierre Anderson

Dr. David Hansson

Dr. Johan Bankefors

Dr. Somer Berigoklu

Dr. Birgit Hakkarainen  

Dr. Lill Kindahl

Dr. Lard Nord

Dr. Nils Nyberg

Selected publications

H.E. Rohnisch, J. Eriksson, LV Tran, E. Mullner, C. Sandström, AA Moazzami. Improved automated quantification algorithm (AQuA) and its application to NMR-based metabolomics of EDTA-containing plasma. Analytical Chemistry, 93, 8729-8738. DOI: 10.1021/acs.analchem.0c04233 (2021).

Bjerketorp J., Levenfors J.J., Nord C., Guss B., Öberg B., Broberg A. Selective isolation of multidrug-resistant Pedobacter spp., producers of novel antibacterial peptides. Frontiers in Microbiology, 12, 642829. doi: 10.3389/fmicb.2021.642829 (2021)

Mullner, E; Rohnisch, HE ; von Bromssen, C; Moazzami, AA. Metabolomics analysis reveals altered metabolites in lean compared with obese adolescents and additional metabolic shifts associated with hyperinsulinaemia and insulin resistance in obese adolescents: a cross-sectional study. METABOLOMICS, 17 (1), DOI: 10.1007/s11306-020-01759-y (2021)

E Alexandersson, C Sandström, LCE Lundqvist, G Nestor , Band-selective NMR experiments for suppression of unwanted signals in complex mixtures.. RSC Advances, 10, 32511-32515, DOI: 10.1039/d0ra06828d, (2020).

Nord, C., Bjerketorp, J., Levenfors, J.J., Cao, S., Strömstedt, A.A., Guss, B., Larsson, R., Hughes, D., Öberg, B., Broberg. A 2020. Isopedopeptins A–H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria. ACS Chemical Biology, 15, 2937-2944. https://doi.org/10.1021/acschembio.0c00568

Rohnisch, HE; Kyro, C; Olsen, A ; Thysell, E ; Hallmans, G ; Moazzami,   AA. Identification of metabolites associated with prostate cancer risk: a nested case-control study with long follow-up in the Northern Sweden Health and Disease Study, BMC MEDICINE, 18  (1), Article Number: 187. DOI: 10.1186/s12916-020-01655-1 (2020)

Agback T; Dominguez F; Frolov I; Frolova EI; Agback P. H-1, C-13 and N-15 resonance assignment of the SARS-CoV-2 full-length nsp1 protein and its mutants reveals its unique secondary structure features in solution. PLOS ONE, 16(12), e0251834. DOI: 10.1371/journal.pone.0251834 (2021)

Lukash T; Agback T; Dominguez F; Shiliaev N; Meshram C; Frolova EI ; Agback P; Frolov I. Structural and Functional Characterization of Host FHL1 Protein Interaction with Hypervariable Domain of Chikungunya Virus nsP3 Protein. Journal of Virology, 95 (1), e01672-20. DOI: 10.1128/JVI.01672-20 (2021).

Wende FJ; Xue Y; Nestor G; Ohrlund A; Sandström C. Relaxation and diffusion of water protons in BDDE cross-linked hyaluronic acid hydrogels investigated by NMR spectroscopy-Comparison with physicochemical properties, Carbohydrate Polymers, 248 (15), 116768, DOI: 10.1016/j.carbpol.2020.116768 (2020)

Bruker Avance III 600 MHz accomodating 120 spinner positions. Photo: Cajsa Lithell.
Bruker Avance III 600 MHz accomodating 30 spinner positions and 5 racks of 96 tubes each. Photo: Cajsa Lithell.
ESI-Ion trap: Amazon Speed ETD. Photo: Cajsa Lithell.

Contact:

Corine Sandström

Professor in Organic Chemistry

+46 (0) 18- 67 15 04

 

Published: 09 May 2022 - Page editor: Henrik.Hansson@slu.se
Loading…